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  By Matteo Satta The commission has been heavily investing in pilot Smart City projects for a long time, but you may often have R&D or innovation projects pretending to have […]
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  Article written by Matteo Satta (Smart) City projects are more and more funded by the European Commission, but consortia often struggle to get cities on board or really engage them. […]
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Massimiliano Mellone

Cambridge, United Kingdom

Member since : Mar 24, 2023

Last activity 1 year ago

Looking for Extra EU Funds

About Me

I am senior scientist at AstraZeneca and Visitor Research Fellow at University of Southampton. I work as in vivo scientist in the Discovery Immuno-Oncology group at at AZ and I have an interest in the Cancer Associated Fibroblasts (CAF) present in the tumour microenvironment. I would like to know more about anything related to CAF and networking with scientists interested in CAFs

Keywords and matching areas:

Biotechnology

Medical Biotechnology

Biology

Ideas in Progress

CAF targeting to boost immuno-therapy

Large Enterprise

Biotechnology

Medical Biotechnology

Biology

Non-responsiveness to immune-checkpoint blockade can result from limited T cell infiltration, mediated by the cells of the tumour microenvironment. Myofibroblastic cancer-associated fibroblasts (myoCAF)-rich tumours generally contain few T-cells and respond poorly to immune-checkpoint blockade. Although myoCAF are associated with poor outcome in most solid tumours, the molecular mechanisms regu...

Cambridge, United Kingdom
1 year ago

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