Search for European Projects

22 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Adhesion switches in cancer and development: from in vivo to synthetic biology (ADHESWITCHES)

Start date: May 1, 2014, End date: Apr 30, 2019,

Integrins are transmembrane cell adhesion receptors controlling cell proliferation and migration. Our objective is to gain fundamentally novel mechanistic insight into the emerging new roles of integrins in cancer and to generate a road map of integrin dependent pathways critical in mammary gland development and integrin signalling thus opening new targets for therapeutic interventions. We will co ...
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 1

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Intergenerational Cumulative Disadvantage and Resource Compensation (INDIRECT)

Start date: Apr 1, 2014, End date: Mar 31, 2019,

"The previous literature has not been able to successfully explain why the loss of the certain family resources does not show as a weaker attainment. Neither the country differences in socioeconomic inheritance seem to reflect the institutional differences between them. We argue that these problems have followed from ignoring resource compensation. The lost capital (economic, human/cultural or soc ...
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 1

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AN INNOVATIVE CAUSAL THERAPY FOR ALLERGY: SAFE AND RAPID INDUCTION OF AN ANTI-INFLAMMATORY IMMUNE RESPONSE USING A MUTANT HYPOALLERGEN AND VITAMIN D3 (BM4SIT)

Start date: Feb 1, 2014, End date: Jan 31, 2019,

Allergy is the most prevalent chronic inflammatory disease, having great socio-economic impact. Chronic lifelong dependency on symptomatic drugs is an expensive reality for the vast majority of allergy sufferers. Allergen-specific immunotherapy is the only causal and effective treatment targeting the underlying immune mechanism in a more cost-effective way. Yet, long treatment duration and risk of ...
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 10

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Personalised Prognostic Tools for Early Psychosis Management (PRONIA)

Start date: Oct 1, 2013, End date: Sep 30, 2018,

Affective and non-affective psychoses have a major negative impact on human society. They account for 6.3% of the global burden of disease and cost €207 billion per year in Europe alone, making them the most expensive brain-related disorders and even more expensive than cardiovascular diseases. This socioeconomic burden is largely caused by two core disease features: onset in adolescence and early ...
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 13

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Personalized diagnosis and treatment of hyperinsulinemic hypoglycaemia caused by beta-cell pathology (BETACURE)

Start date: Apr 1, 2014, End date: Mar 31, 2018,

Background:Hyperinsulinaemic hypoglycaemia (HH) is a potentially lethal disease caused by over functioning beta cells derived from the pancreatic islets of Langerhans. Lethal HH and brain damage is a problem especially in infants with congenital HH. Current therapeutic approaches are associated with severe side effects/morbidity (diabetes, exocrine pancreas insufficiency etc.) considered acceptabl ...
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 17

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Ark of Inquiry: Inquiry Awards for Youth over Europe (Ark of Inquiry)

Start date: Mar 1, 2014, End date: Feb 28, 2018,

The Ark of Inquiry project aims to raise youth awareness to Responsible Research and Innovation (RRI) by providing young European citizens (7 to 18-year-olds) with a pool of engaging inquiry activities to improve their inquiry skills, increase their awareness and understanding of conducting ‘real’ science, and prepare them to participate in different roles in the European research and innovation p ...
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 13

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Academia-Industry Research and Development Opportunities for Picornaviruses (AIROPico)

Start date: Jan 1, 2014, End date: Dec 31, 2017,

Viruses belonging to the large family of Picornaviridae such as enteroviruses, rhinoviruses and parechoviruses represent the most commonly encountered infectious agents in mankind. Several research groups in Europe are active on different aspects of picornavirus research. Nevertheless, prevalence, transmission, and pathogenesis are still largely unknown and no therapy is available for picorna infe ...
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 10

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Exploring Functional and Developmental Osteoclast Heterogeneity in Health and Disease (EUROCLAST)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

Euroclast proposes a research training program on osteoclast biology in the context of osteoclast-driven diseases. Osteoclasts are the complex, multinuclear cells responsible for bone breakdown. Many diseases of osteoclast malfunctioning manifest in bone loss, for example, osteoporosis, cancer-induced bone disease, periodontitis, or rheumatoid arthritis, all conditions set to increase in an ageing ...
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 11

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Development of very promising humanized therapeutic mAbs efficiently neutralizing a novel immunosuppressive pathway involved in a wide range of cancers (TumAdoR)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

Studies have demonstrated the importance of CD73 in the spread of cancer. Overexpressed in numerous cancer types, this enzyme leads to the production of high amounts of extracellular Adenosine, creating an immunosuppressive microenvironment, and contributing to tumor proliferation and dissemination. Neutralizing its activity represents a highly potent and innovative therapy.Following on the recent ...
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 8

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Brain Imaging Return to Health (r'BIRTH)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

Extended lifespan is a new and permanent feature of human life globally. The demographic for population growth of persons over 60 years is predicted to expand by 70% and 400% respectively in developed and less developed regions during the coming decades. Ageing, is accompanied by cognitive decline and greater risk of depression and anxiety. Major drug companies have recently cutback significantly ...
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 10

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Ports Observatory for Performance Indicator Analysis (PORTOPIA)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

PORTOPIA aims to develop, next to extensions of existing indicators within the different perspectives of port performance, innovative approaches for the industry's stakeholders, such as:• Development of a forecasting dimension in port performance management within the market trends and structure category;• Development of top-down methods for harmonised socio-economic impact calculation;• Developme ...
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 12

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Neuroimaging platform for characterisation of metabolic co-morbidities in psychotic disorders (METSY)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

"The theme of this collaborative project is development and application of neuroimaging and bioinformatics tools to study lipid metabolism as a common pathogenic link between psychotic disorders and its metabolic co-morbidities. The overall objective is to identify, prioritize and evaluate multi-modal blood and neuroimaging markers with diagnostic potential for prediction and monitoring of psychot ...
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 13

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Direct Ethanol from MicroAlgae (DEMA)

Start date: Dec 1, 2012, End date: May 31, 2017,

"The DEMA Consortium will develop, demonstrate and licence a complete economically competitive technology for the direct production of bioethanol from microalgae with low-cost scalable photobioreactors by 2016. Initial proof-of-concept results show via Life Cycle Assessments (LCA) and economic balance that it is feasible to use microalgae to produce bioethanol for less than € 0.40 per litre. The c ...
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 10

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Biological Foundation for the Safety Classification of Engineered Nanomaterials (ENM): Systems Biology Approaches to Understand Interactions of ENM with Living Organisms and the Environment (NANOSOLUTIONS)

Start date: Apr 1, 2013, End date: Mar 31, 2017,

The main objective of this research proposal is to identify and elaborate those characteristics of ENM that determine their biological hazard potential. This potential includes the ability of ENM to induce damage at the cellular, tissue, or organism levels by interacting with cellular structures leading to impairment of key cellular functions. These adverse effects may be mediated by ENM-induced a ...
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 40

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Interferon-beta treatment of acute respiratory distress syndrome (ARDS) (TRAUMAKINE)

Start date: Dec 1, 2012, End date: Nov 30, 2016,

This application aims at a European marketing application for an orphan indication of the biopharmaceutical interferon-beta (IFN-beta) (EU3/07/505), to treat acute lunge injury (ALI) and acute respiratory distress syndrome (ARDS). Despite the much improved mechanical ventilation techniques and improved supportive therapies, ARDS kills 35-40 % of the 175.000 annual European patients. This condition ...
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 5

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Innovative Radiochemistry to Advance Molecular Imaging (RADIOMI)

Start date: Nov 1, 2012, End date: Oct 31, 2016,

The RADIOMI Initial Training Network (ITN) has the goal of providing training in a superbly suited academic and industrial environment uniquely equipped to conduct a scientific research program that addresses one of the key aspects of functional imaging, the underpinning radiochemistry essential for preparation of radiotracers currently difficult or not possible to access. This will be exploited f ...
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 9

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Design & Engineering of Photosynthetic Communities for Industrial Cultivation (PHOTO.COMM)

Start date: Oct 1, 2012, End date: Sep 30, 2016,

The generation of young biotechnologists is of paramount importance for Europe´s future. PHOTO.COMM will train primarily early stage researchers who have demonstrated high ambitions and talents in a unique platform based on emerging technology and science that would shape the forefront of future European biotechnology. PHOTO.COMM involves the utilization of microalgae for the conversion of carbon ...
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 11

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Cancer Associated Fibroblasts (CAF) Function in Tumor Expansion and Invasion (CAFFEIN)

Start date: Oct 1, 2012, End date: Sep 30, 2016,

"Aim of the CAFFEIN network is to provide 10 early stage researchers (ESRs) and 2 exprerienced researchers (ERs) with excellent training in an industry relevant area of cancer research, complementary skills required for pharmaceutical industry, and knowledge in setting up biomedical start-up companies. To this end, the network comprises two full industrial partners: the established pharmaceutical ...
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 11

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A new therapeutic antibody with a personalised medicine approach in cardiovascular disease (CARDIMMUN)

Start date: Aug 1, 2013, End date: Jul 31, 2016,

"The project, CARDIMMUN, aims to pursue development of the scientific findings from the FP6 project CVDImmune. Based on our patented discovery, that low levels of anti-PC (phosphorylcholine) indicate risk for future development of cardiovascular disease, we have developed both a diagnostic test (a marker to identify cardiovascular disease patients that are at high risk of secondary events) and a c ...
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 5

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Direct photobiological conversion of solar energy to volatile transport fuels (PHOTOBIOFUEL)

Start date: Jan 1, 2011, End date: Dec 31, 2015,

The aim is to integrate photosynthetic solar energy conversion and synthesis of volatile engine-ready transport fuel in a single photobiological process. The focus is placed on the construction of phototrophic model systems for synthesis of the short-chain alkane propane (C3H8). Propane can be used in existing engines without further chemical conversion and can be easily recovered from the product ...
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 3

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Advanced Radio Astronomy in Europe (RADIONET3)

Start date: Jan 1, 2012, End date: Dec 31, 2015,

RadioNet is an I3 that coordinates all of Europe’s leading radio astronomy facilities in an integrated cooperation to achieve transformational improvement in the quality and quantity of the scientific research of European astronomers. RadioNet3 includes 27 partners operating world-class radio telescopes and/or performing cutting-edge R&D in a wide range of technology fields important for radio ast ...
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 29

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Infrastructure for Systems Biology - Europe (ISBE)

Start date: Aug 1, 2012, End date: Jul 31, 2015,

...the needs of European systems biology, in terms of development, applications and training. In order to address this requirement, we are proposing a distributed, interconnected infrastructure which primarily comprises three types of centres: Data Integration Centres (DICs), and systems biology dedicated Data Generation Centres (DGCs), and Data Stewardship Centres (DSCs). DICs are research centres t ...
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