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Therapeutic Applications of Light-Regulated Drugs (THERALIGHT)
Start date: Aug 1, 2013, End date: Nov 30, 2014 PROJECT  FINISHED 

One of the major drawbacks of pharmacological therapies is the difficulty to control drug kinetics and restrict drug action to the target organ. This in turn limits the efficacy of drugs and triggers undesired side effects for patients. We have developed an innovative approach to control the activity of drugs with light in cell culture systems. The PoC grant will allow going a step further by testing these new methods on important pharmacological target receptors and assay them in vivo. These tests should lead to the first clinical trials and to present the biomedical applications of his project to pharmaceutical companies. The combination of drugs with external illumination devices could create a more personalised medicine where therapies could be tuned to adapt each individual patient.
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