Tailored biodegradable magnesium implant materials
Start date: Oct 1, 2011,
End date: Sep 30, 2015
Cost reduction and improvement of the quality of life is a major issue in health care. This challenge can be tackled by intelligent biomaterials and smart implants which are resorbed by the body upon remodelling of the tissue: What is possible for polymer materials should also be realized for biodegradable metallic materials. MagnIM will train 12 ESRs to contribute to this demanding aims by the development of new aluminium free Magnesium implant materials with tailored properties specific for a bone related application especially in children and for sport medicine. To reach this goal carefully selected materials and processing routes will be combined with comprehensive research to elucidate the correlation between microstructure and corrosion processes. This will be monitored in vitro and in vivo. The ultimate goal will be a prototype implant design which is based on the achievements of this network. To do this, the specific combination of the MagnIM research team is necessary. MagnIM brings together world leading scientists from various research fields: Material scientists and engineers who develop new alloys with tailored properties for biomedical applications and medical scientists and biologists researching on macro- and microscopically changes in bones and bone cells with in vitro and in vivo methods. MagnIM collectively covers basically all aspects, instrumental techniques and approaches necessary to tackle successfully the challenge to understand, and ultimately control, interactions at the material – bone interface. The full achievements of this research are gained because the consortium covers the full value chain from fundamental engineering research towards implant production including relevant industry partners and clinics.
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