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Novel natural antimicrobial agents for bacterial pathogen control (NNAA)
Start date: Jan 31, 2013, End date: Jul 30, 2014 PROJECT  FINISHED 

Antimicrobial agents have extremely reduced the number of deaths from previously widespread and fatal infectious diseases. As a result of inappropriate use of antibiotics, bacteria have developed various mechanisms of resistance and the multiple resistant bacteria nowadays fail to respond to conventional treatment and significantly increase risk of death. European Commission has recently proposed a strategy to combat antimicrobial resistance and one of the main aims is development of effective antimicrobials or alternatives for treatment of bacterial infections.The aim of the 18-months long project is to test the usability of certain bacterial viruses (bacteriophages) for bacterial pathogen control and to examine cyanobacterial extracts as potential source of novel natural antimicrobials. Bacteriophages and cyanobacteria are to be isolated from environment in the crossborder region, screened for antimicrobial activity against various pathogen bacteria and characterized using appropriate microbiological, toxicological and molecular methods.In the transborder research project, University of Novi Sad and University of Szeged are involved, both with well defined roles. The outputs of the project are contribution to overcoming the problem of multiple resistance through discovering new natural antimicrobials, establishment of well characterized collection of bacteriophages and cyanobacteria as well as increasing awareness of multiple resistant bacteria on both sides of the border. Achievements: Uncontrolled consumption of antibiotics resulted in the emergence of multiple and pan-resistant bacteria. As a result, infections caused by these bacteria cannot be treated with conventional antibiotics. The project partners aim was to test the usability of certain bacterial viruses (bacteriophages) for bacterial pathogen control and to examine cyanobacterial extracts as a potential source of novel natural antimicrobials. It should be emphasised that the NNAA project, by discovering new natural antimicrobials, wanted to play a role in overcoming the problem of bacterial multiple resistance, which is recognised by the EU as one of the main health concerns. Beside the innovative research work, the project partners held an opening event and a meeting in Novi Sad, plus a seminar in Szeged. The project improved the long-lasting and mutually beneficial cooperation between the partner institutions, and also increased awareness of the problem of multiple resistant bacteria among experts and the general public through media appearances and the distribution of information materials about the project activities.

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