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Multi-disciplinary biodosimetric tools to manage high scale radiological casualties (MULTIBIODOSE)
Start date: May 1, 2010, End date: Apr 30, 2013 PROJECT  FINISHED 

"In the event of a large scale radiological emergency biological dosimetry is an essential tool that can provide timely assessment of radiation exposure to the general population and enable the identification of those exposed people, who should receive medical treatment. A number of biodosimetric tools are potentially available, but they must be adapted and tested for a large-scale emergency scenario. These methods differ in their specificity and sensitivity to radiation, the stability of signal and speed of performance. A large scale radiological emergency can take different forms. Based on the emergency scenario different biodosimetric tools should be applied so that the dosimetric information can be made available with optimal speed and precision. The aim of this multi-disciplinary collaborative project is to analyse a variety of biodosimetric tools and adapt them to different mass casualty scenarios. The following biodosimetric tools will be validated and established: the dicentric assay, the micronucleus assay, the gamma-H2AX assay, the skin speckle assay, the blood serum protein expression assay and EPR/OSL dosimetry in components of pocket electronic devises. The assays were chosen because they complement each other with respect to sensitivity, specificity to radiation and the exposure scenario as well as speed of performance. The project will involve the key European players with extensive experience in biological dosimetry. Training will be carried out and automation and commercialisation pursued. An operational guide will be developed and disseminated among emergency preparedness and radiation protection organisations. The final deliverable of this project will be establishment of a biodosimetric network that is fully functional and ready to respond in case of a mass casualty. Thus, the project will strengthen the European security capabilities by achieving tangible results."
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