Τhe research conducted as part of the school self-evaluation has revealed that there is need for systematic in-service training in modern teaching approaches and the relevant methodology so that the best way of providing knowledge and the full development of students may be achieved and the school will meet the requirements imposed by its role and special character as the Pilot Experimental Senior High School of the University of Crete. The general aim of the project is to upgrade the quality of the provided educational service and enrichment of the teaching by adopting innovative teaching methods which are effective in dealing with new phenomena, such as the internationalization of education, will support the creation of flexible learning models and ensure the certification of skills and qualifications of the teaching staff. Twenty (20) teachers in various disciplines will participate in this project and they will be trained in the following: 1. "Interactive teaching - Using educational games in order to enhance learners motivation" aiming at integrating non-formal learning and its tools in formal learning, 2 . «Problem based learning / Inquiry based learning» aiming at linking theory up with practice and developing students' critical thinking with the help of innovative methods, 3. «STRUCTURED STUDY VISITS» aiming at the acquaintance with foreign educational systems , the organization and the operation of schools abroad and the cooperation of the school with intergovernmental organisations, and, finally, its opening to both the local and the international community, 4. «Innovative approaches to teaching» aiming at the introduction of innovation in teaching practices. The methodology for carrying out the project includes the investigation of the teachers’ needs, the satisfaction of these needs through in-service training, the evaluation, the experimental application of the programme, the gradual integration of innovative teaching practices in school life and, last but not least, dissemination of the information about good practices in the wider educational community. Regarding the results, teachers will learn innovative teaching methods, become familiar with the use of differentiated instruction and pupils’ motivation techniques, develop skills of critical and creative thinking and taking initiative, develop a sense of confidence about the application of new techniques in their classes, exchange ideas concerning education in the modern world, take on a more active role in the educational community and promote the international openness of the school. The impact of the project regarding the staff of the school will be assessed with reference to the adoption of a student-centred approach and the change of teachers’ role in the teaching practices. As far as the pupils are concerned, it will be assessed with reference to their academic performance and full development as personalities. Finally, this project will raise the quality of the educational work, boost the school prestige and open up cooperation opportunities with local as well as European institutions.