This project conducts research on the design and implementation of scalable hypervisors for emerging and future multi-core systems. The scientific objective is to develop a new hypervisor that enables synthesis of customized application execution environments, while leveraging new hardware capabilities, such as computation accelerators and software-controlled, configurable layout of processor cores. The proposed hypervisor, I-cores, is designed to empower system software with novel performance and energy optimizations that permeate the entire software stack. The project plan includes knowledge transfer activities that will assist the migration of the research environment of the applicant from the United States, where he is currently employed as a tenured faculty member, to the European space. The project will also carry out educational activities that advance the concept of virtualization in computer and information science, and broader impact activities that will apply innovative virtual computing infrastructures to address the computing needs of sensitive sectors, including education and healthcare.