Exploring the glycosylation process during infecti.. (Infection glycomics)
Exploring the glycosylation process during infection
Start date: Jan 21, 2008,
End date: May 9, 2012
Cellular Glycosylation is a finely tuned process that is very suscpetible in changes due to environmental stimuli. We have preliminary data showing that intestinal infections in mice and rats are capable in changing the glycosylation profile of intestinal glycoproteins. We speculate that this could be due to a translational regulation of glycosyltransferases. Hence, we would like to use RT-PCR and quantiative proteomic to identify specific glycosyltransferases affected by the infection cycle.
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