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Comparative Genomics and Next Generation Sequencing (COGANGS)
Start date: Nov 1, 2010, End date: Feb 28, 2013 PROJECT  FINISHED 

"The activity of genes is absolutely essential for all life – from viruses and bacteria to crops and human beings. Despite the many technological breakthroughs within life science research during the last 20-30 years, we are however still far away from fully understanding the activity of genes and which factor influence (regulates) the gene activity. Such knowledge is, by nature, of very high importance and very high value to life science researchers globally, and the ANGS project consortium will therefore develop a suite of algorithms, methods, and software tools that are significantly better at analyzing and understanding gene regulation than what exists today. The consortium consists of three SMEs that all are poised to take advantage of the new developments in genome sequencing (CLC bio, BIOBASE, and deCODE genetics), and 4 academic partners (Oxford University, Goettingen University, Renyi Institute, and NCSB). The SMEs will commercialize the results to help ensure that EU companies are established among the world leaders within solutions for analysis of gene regulation. The primary focus of the consortium will be to develop methods for including the massive amounts of genomic data that is being generated using the revolutionary Next Generation Sequencing technologies – an amount of data that will increase exponentially in the coming years, and that is virtually impossible to analyze with any reasonable success by existing methods and in existing software. The software suite, the ANGS engine will thus make it possible to include up to a thousand genomes, e.g. from the 10,000 genome project as knowledge input in gene regulation analysis. Such software will be able to provide completely new knowledge and will thus have tremendous value to life science researcher globally, including pharmaceutical companies, biotech companies, agricultural companies, biofuel companies, research hospitals, as well as universities and governmental research organizations"

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