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Cerebral representation of object-location memory (Spatial memory)
Start date: Jan 1, 2011, End date: May 30, 2016 PROJECT  FINISHED 

The uptake and recall of arbitrary associations between objects and their spatial location is a core feature of spatial memory. This form of learning is fundamental to survival across the phylogenetic spectrum. Nevertheless, the hemispheric organization of this function has yet to be understood. Whilst object-location memory is one component of spatial memory most consistently lateralized to the right mesial temporal region, recent research on neurologically healthy participants suggests the existence of task-specificity within the object-location paradigm. Our aim in this project is to investigate the lateral cerebral representation of object-location memory, focussing on two distinct process mechanisms: object processing and spatial-location processing. We propose to study unoperated patients with well-lateralized mesial temporal lobe epilepsy (TLE) with the use of functional Magnetic Resonance Imaging (fMRI) and intracranial EEG recording.
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