Search for European Projects

An Integrated Computational and Spectroscopic Investigation of the Enzyme Mechanism of Tryptophan Hydroxylase (ICSTH)
Start date: May 16, 2011, End date: Jul 31, 2014 PROJECT  FINISHED 

"Metalloenzymes play crucial role in neurobiology and therefore they are very important target for drug design for treatment neuropathological processes. In order to make new specific and effective drugs it is crucially important to understand the structure and functions of their drug targets. In this Outgoing Marie Curie Fellowship application we propose combined computational/spectroscopic investigation of the enzyme mechanism of tryptophan hydroxylase – a pterin-dependent non-heme containing iron enzyme in crucial importance for the nervous system. Accurate insight in the mechanism of such a complicated enzyme can not be received using solely computational or experimental methods therefore we will apply integrated combination of state-of-the-art computational methods with most modern spectroscopy methods (e.g. K edge X-ray Absorption Spectroscopy, Magnetic Circular Dichroism and variable-temperature variable-field MCD, and EPR). The results will provide understanding of the structure-functions relationships of this enzyme and will be used in drug design."
Up2Europe Ads
Ana Maria Solis

 Erasmus+
 Horizon Europe

Expert - Project Development & EU Funding Consultant in participatory processes 

MY SUCCESSFUL EXPERIENCES IN COMMUNITY GRANTS

Angelo Napolitano

 Partnership Management
 Transnational cooperation

Seeking to stimulate and improve the participation of Italian private and public stakeholders to EU projects
Nuno Vaz Silva - C Consulting

 Creative Industries
 INTERREG

Expertise in EU projects and policies – drafting project proposals, technical and administrative assistance, support to project implementatio ...

ONECO

 Erasmus+
 International Project Management

ONECO is a consultancy of European programs in the field of education, culture, employment and local development. From 1997 until ...

Marketkaps

 Horizon Europe
 LIFE programme

Marketkaps Senior Consultants are former Entrepreneurs and also Experts & Auditors for the European Commission (Horizon Europe, Eureka) and Fre ...

Ing. Iva Mládenková PhD

 Horizon Europe
 Innovation & Research

Freelance EU funding analyst and consultant - Focused primarily on EU Direct Management Programmes, in particular H2020, Eras ...

Jose Ospina Development Consultant

 Eco-Innovation
 Energy Efficiency

I have worked for over 35 years in a professional capacity in as  project developer and manager in areas related to sustainable development an ...

Joanna Elwira Sychta

 Entrepreneurship and SMEs
 Project Management

Developing and managing the R&D applications of the European Union Funds especially Horizon 2020 SME Instrument, Marie Curie Research and other ...

Coordinator

Details