Search for European Projects

26 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Zinc Interaction with Phosphorus in Root Uptake (ZIPRU)

Start date: May 1, 2015, End date: Apr 30, 2017,

"The overall goal of this project is to understand phosphorus (P) and zinc (Zn) interactions in the mineral nutrition of Brassica oleracea, a species that has been bred into a wide range of crops such as broccoli, cabbage, kale and cauliflower. To achieve this, we will develop a comprehensive understanding of key mechanisms and coordination of P-Zn cross-talk that allows high P-use-efficiency (PUE ...
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 1

 FINISHED 

Tele-Cardiology in the Greek-Albania Borderline (Telecardiology)

Start date: Apr 30, 2012, End date: Oct 30, 2013,

The proposed project is built around the needs described on the SWOT analysis provided in the Programme documents, aiming to use the identified strengths (high training and expertise of medical experts), in order to tackle the weaknesses (lack of cooperation and access restraints) and use telemedicine, specifically telecardiology, so as to increase the standard of living of the population by prom ...
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 3

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IF LAB

Start date: Dec 1, 2015, End date: Nov 30, 2016,

!IF LAB 2016 is designed to help creatives to produce and develop their online factual interactive stories.!FLAB 2016 provides 3 x 4 days workshops geared at helping teams to get through the ideation, design and coding phase of their project – via constant testing, prototyping and experimentation. The emphasis in iterative creative design and in user experience (applied to storytelling).Participan ...
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 1

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IF LAB

Start date: Dec 1, 2014, End date: Nov 30, 2015,

IF Lab is designed to help creatives to produce and develop their online factual interactive stories.Interactive factual stories can be any creative project that uses digital interactive media to portray factual issues: online journalism, i-docs (interactive documentaries), serious games, historical graphic novels for the iPad, media rich NGO websites, museum installations or locative and educat ...
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 1

 FINISHED 

Patrimoniul gastronomic european

Start date: Oct 1, 2014, End date: Sep 30, 2016,

The mobility project is organized by "Mihail Kogalniceanu" Economic College in Focsani, Romania, in partnership with Llandrillo- Menai College in Rhos-on-Sea, Wales. The "European gastronomic heritage" project’s target group is represented by 30 students in the field of Travel and Food service, class X, undergoing practical training modules "Assortment of dishes and drinks" and "Serving preparati ...
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 2

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High-Resolution X-ray Structures of Full-Length Cystic Fibrosis Transmembrane Conductance Regulator (CF_struct)

Start date: Nov 16, 2016, End date: Nov 15, 2018,

This proposal seeks to solve the high-resolution X-ray crystal structure of full-length Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), an anion channel which regulates chloride ion concentration at the lumen-exposed surface of epithelial cells. Mutations of the CFTR gene cause cystic fibrosis (CF), a lethal disease which results in bowel obstruction, lung disease and premature death. ...
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 1

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Anchoring ligandable binding sites at E3 ligase surfaces for plug-and-play PROTACs. (ANCHOR E3s)

Start date: Aug 1, 2016, End date: Jul 31, 2018,

The Anchor E3s project proposes to establish, for the first time, an efficient protocol for the discovery and characterisation of accessible binding sites at any patch of a protein surface, regardless of its involvement in biological function. One of the motivation of the research is to develop a general approach to discover new “anchor” ligands that can enable improved plug-and-play proteolysis t ...
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 1

 FINISHED 

Optimization and scale-up of final sealing of Sulfuric Acid Anodizing employing Design of Experiments. (SEALANT)

Start date: Jul 1, 2016, End date: Jun 30, 2018,

Chromic Acid anodizing (CAA) of aluminium parts has been extensively used during decades in aircraft manufacturing thanks to its excellent performance. However, hexavalent chromium is known to be carcinogenic and harmful for the environment. The main objective of the topic to which the present proposal relates is to optimize a Chromium-free sealing process for thin layer Sulfuric Acid Anodizing (S ...
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 5

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Highly porous collagen scaffolds for building 3D vascular networks: structure and property relationships (3DSTAR)

Start date: Nov 14, 2016, End date: Nov 13, 2018,

This proposal concerns with the development of functional 3D hierarchical vasculature within engineered freeze-dried collagen scaffolds. The main objective is to investigate the contribution of scaffold’s pore architecture (size, shape and interconnectivity) and culture conditions, such as cell ratios in co-culture, perfusion vs. static culture and hypoxia, on the self-organisation of endothelial ...
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 1

 FINISHED 

Barrel Assemblies of Membrane Active Artificial Foldamers (BARREL)

Start date: Aug 1, 2015, End date: Jul 31, 2017,

Development of resistance by bacteria to antibiotics makes design of novel antimicrobial compounds increasingly important. As persistent cells often become slow-growing or dormant, strategies targeting their membrane are becoming more relevant. For several natural antimicrobial peptides function can be coupled to scaffolds with high sheet content. Toxic oligomers may assemble into hydrophilic or l ...
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 2

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The molecular basis of CULLIN E3 ligase regulation by the COP9 signalosome (CsnCRL)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

Specificity in the ubiquitin-proteasome system is largely conferred by ubiquitin E3 ligases (E3s). Cullin-RING ligases (CRLs), constituting ~30% of all E3s in humans, mediate the ubiquitination of ~20% of the proteins degraded by the proteasome. CRLs are divided into seven families based on their cullin constituent. Each cullin binds a RING domain protein, and a vast repertoire of adaptor/substra ...
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 1

 FINISHED 

Scattered radiation reduction tool to improve computer-aided diagnosis performance in digital breast tomosynthesis (SCARtool)

Start date: Sep 1, 2015, End date: Aug 31, 2017,

Breast cancer is the most common cancer diagnosed in women worldwide. This has motivated the establishment of breast screening (BSPs). X-ray mammography is the current gold standard technique in BSPs for early breast cancer detection. However, this technique suffers from performance limitations due to tissue superposition which can either mimic or obscure malignant pathology. For this reason digit ...
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 1

 FINISHED 

CryoEm structure of gamma secretase: a key component in Alzheimer neurodegenerative disease (Renzi_FP7_IOF2007)

Start date: Oct 1, 2008, End date: Sep 30, 2011,

Alzheimer disease (AD) is characterised by the accumulation of beta amyloid peptide cut from a transmembrane precursor. A large intramembrane complex carries out the proteolysis: gamma-secretase, containing the protease presenilin and other three proteins (nicastrin, aph1, pen2). G-secretase is involved also in the proteolysis mediated signaling cascade by the transmembrane receptors Notch1 and Er ...
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 1

 FINISHED 

Social Network Implementation of Health Campaigns Among Youth (SNIHCY)

Start date: Sep 1, 2014, End date: Aug 31, 2019,

"Western societies devote substantial resources to media health campaigns, especially targeting young people. Unfortunately, health campaigns often have disappointing impact. There is a compelling need for insight into campaign implementation in social life. Especially among youth, the social environment plays a crucial role in message processing. Therefore, health campaigns can only be improved w ...
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 1

 FINISHED 

Cross-Coupling (C-X): Pioneering Mild Aqueous Cross-Coupling Methodologies to Enable Selective Functionalisation and Diversification of Halogenated Natural Products (C-Xaq)

Start date: May 1, 2015, End date: Apr 30, 2017,

Natural Products (NPs) are key to medicine, yet the generation of analogues of these important compounds can often be challenging. I propose to investigate an exciting new approach to NP analogues pioneered by the Goss lab. By developing new, mild, aqueous and selective cross-coupling chemistries I will enable the selective diversification of organic molecules, and in particular NPs, containing ca ...
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 1

 FINISHED 

RNA Polymerase III Rpc4/Rpc5 subcomplex and Selenocysteine tRNA transcription (Human Rpc5)

Start date: May 1, 2015, End date: Apr 30, 2017,

In higher eukaryotes, the RNA polymerase III (Pol III) participates in the transcription of small RNAs such as the tRNAs. RNA polymerase recruitment to their specific promoter relies on the activity of several transcription factors. Brf2 is a transcription factor that exclusively recruits RNA Pol III at the selenocysteine tRNA (tRNASec). Unpublished work from our group has unravelled an unanticipa ...
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 1

 FINISHED 

Nanobody-enabled Structural Investigation of a G Protein-Coupled Receptor-Arrestin Complex (NESIAC)

Start date: Jul 1, 2015, End date: Jun 30, 2017,

Although many thousands of transient protein-protein interactions (PPIs) are known, there is a disturbing paucity of high-resolution structures of the resulting complexes and the difficulties involved in experimentally determining these atomic structures remain essentially unaddressed.The Steyaert lab has shown that cross-linking transiently interacting proteins, followed by immunization of llama’ ...
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 1

 FINISHED 

Chromosome structure and genome organization in early mammalian development (DEVOCHROMO)

Start date: Feb 1, 2014, End date: Jan 31, 2019,

"The spatial organization of the genome inside the cell nucleus is tissue-specific and has been linked to several nuclear processes including gene activation, gene silencing, genomic imprinting, gene co-regulation, genome maintenance, DNA replication, DNA repair, chromosomal translocations and X chromosome inactivation. In fact, just about any nuclear/genome function has a spatial component that h ...
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 1

 FINISHED 

Membrane Protein Nanocrystallography (NanoMem)

Start date: Jan 1, 2013, End date: Dec 31, 2016,

Modern structural biology builds upon synergies between lab-bench scale science on the one hand and large scale research infrastructure on the other. NanoMem recognises the transformative opportunities that are created by current X-ray source and detector developments to impact strongly on membrane protein structure, a challenging sub-field of structural biology. We will exploit synchrotron based ...
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 11

 FINISHED 

RNA poly(A) tail: the beginning of the end (DEAD2THEEND)

Start date: Apr 1, 2012, End date: Mar 31, 2017,

"The degradation of mature mRNAs has emerged as a key step in the regulation of eukaryotic gene expression. Modulation of the half-life of mRNAs via their degradation is a powerful and versatile mechanism to swiftly alter the expression of proteins in response to changes in physiological conditions. The decay of mRNAs is performed by a set of macromolecular complexes that act in a sequential and c ...
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 1

 FINISHED 

Chemical evaluation of drinking water disinfection byproducts (ChE-WADISBYPRO)

Start date: Jan 16, 2012, End date: Jan 15, 2015,

Disinfection byproducts (DBPs) are generated when disinfectants such as chlorine, ozone, chloramine, or chlorine dioxide, react with natural organic matter and/or bromide/iodide present in source waters, and they may pose health risks. Despite intense research carried out in this field, more than 50% of the total organic halogens formed during water disinfection still remain unidentified. Addition ...
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 2

 FINISHED 

Characterization of the molecular components of synapses in Fragile-X mental retardation syndrome: new insights into the FMRP regulatory mechanisms (Synapses FXS)

Start date: Jun 1, 2011, End date: May 31, 2013,

Fragile-X mental retardation syndrome (FXS) is caused by mutations in the Fmr1 gene that codes for the FMRP protein. FMRP is an RNA binding protein involved in mRNA metabolism. The translational dysregulation of a subset of FMRP target mRNAs is probably the major contribution to FXS. A hallmark of the FXS phenotype is the elevated spine density with immature morphology. We aim to understand the ca ...
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 1

 FINISHED 

Effects of Different Learning Experiences on Automatic Evaluative Processes (DLEAEP)

Start date: Apr 1, 2010, End date: Mar 31, 2014,

"In evaluative learning, associative learning refers to the effect of repeated exposure to an object and an evaluation that appear together (e.g., “Snakes-Unpleasantness”), whereas propositional learning refers to learning the actual relationship between the object and the evaluation (e.g., “Snakes cause unpleasantness”). A common core assumption in contemporary attitude research is that associati ...
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 1

 FINISHED 

Overlooked Unresolved Toxic Organic Pollutants: Resolution, Identification, Measurement and Toxicity:OUTREACH (OUTREACH)

Start date: Jul 1, 2009, End date: Dec 31, 2014,

Organic pollution exceeds an area greater than that of France+Germany. Toxic, persistent, unresolved and unidentified, complex mixtures (UCMs) of organic chemicals are abundant all over the globe. These UCMs, which encompass a number of chemical classes, are outside present EU and world pollutant regulations. It is very important that these toxicants are identified, measured and their effects stud ...
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 3

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Critical Infrastructure Protection using Adaptive MILS (CITADEL)

Start date: Jun 1, 2016, End date: May 31, 2019,

Critical infrastructures (CI) rely on complex safety- and security-critical ICT systems placed into unpredictable environments and forced to cope with unexpected events and threats while exhibiting safe adaptive behavior. Recent security trends stress continuous adaptation to increase attacker work factor and to confound reverse-engineering. Critical CI systems must undergo extensive and costly sc ...
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 14

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UCOACH. Executive Coaching for SME's

The objective of U-COACH was the development of the skills and competencias necesary to integrate and apply Executive Coaching techniques in the human resource and personnel management team processes. Managers, of all levels, and entrepreneurs of European SMEs have obtained, through the creation of a learning methodology, the relevant skills to improve the performance and competitiveness of their ...
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 8