2 European Projects Found
Searched on 125080 European Projects
FINISHED
Epigenetic Disruption of Non-Coding RNAs in Human Cancer (EPINORC)
Start date: Apr 1, 2011, End date: Mar 31, 2016,
In recent years, my laboratory, as well as others, have established the observation that epigenetic disruption, particularly in the DNA methylation and histone modification patterns, contributes to the initiation and progression of human tumors (Esteller, Nat Rev Genet 2007; Esteller, N Engl J Med 2008; Esteller, Nat Rev Biotech, In Press, 2010). Even more recently, it has been recognized that mic ...
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FINISHED
Determining (epi)genetic therapeutic signatures for improving lung cancer prognosis (CURELUNG)
Start date: Jan 1, 2011, End date: Jun 30, 2014,
"Lung cancer (LC) is still the most lethal type of cancer worldwide. The extremely poor prognosis for LC patients is partly due to the lack of effective therapies. At present, most patients with pulmonary carcinomas are treated with chemotherapy. This essentially consists of classic cytotoxic drugs which only improve survival in small cohorts in few cases. In spite of the rapidly growing understan ...
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