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Regulation of dopamine transporter function by the PDZ domain protein PICK1 (PICK1 and DAT)
Start date: Jun 1, 2008, End date: May 31, 2010,
The dopamine transporter (DAT) belongs to the family of Na+/Cl- dependent neurotransmitter transporters and is responsible for rapid termination of dopaminergic signaling by mediating reuptake of dopamine (DA) from the synaptic cleft. The DAT is target for widely abused psychostimulants, such as amphetamine and cocaine, as well as modification in DAT activity has been associated with severe brain ...
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