Search for European Projects

Over 40 European Projects Found

Searched on 125080 European Projects

 FINISHED 

REgenerative therapy of intervertebral disc: a double blind phase 2b trial of intradiscal injection of mesenchymal stromal cells in degenerative disc disease of the lomber SPINE unresponsive to conventional therapy (RESPINE)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

The World Health Organisation (WHO) has included low back pain in its list of twelve priority diseases. Notably, Degenerative disc disease (DDD) presents a large, unmet medical need which results in a disabling loss of mechanical function. Today, no efficient therapy is available. Chronic cases often receive surgery, which may lead to biomechanical problems and accelerated degeneration of adjacent ...
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 18

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Characterisation Of A Green Microenvironment And To Study Its Impact Upon Health and Well-Being in The Elderly As A Way Forward For Health Tourism. (CHARMED)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

Our society in Europe is still under prepared for the demographic changing situation of an ageing population which began several decades ago. This is visible in the age structure of the population and is reflected by the fact that the population aged 65 years and over is increasing in every European country. The growth in the elderly population may be explained by increased longevity, but at the s ...
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 19

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Ubiquitous Pharmacogenomics (U-PGx): Making actionable pharmacogenomic data and effective treatment optimization accessible to every European citizen (U-PGx)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

Pharmacogenomics is the study of genetic variability affecting an individual’s response to a drug. Its use allows personalized medicine and reduction in ‘trial and error’ prescribing leading to more efficacious, safer and cost-effective drug therapy. The U-PGx consortium will investigate a pre-emptive genotyping approach (that is: multiple pharmacogenomic variants are collected prospectively and ...
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 16

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NOVEL, SUSTAINABLE MARINE BIO-SURFACTANT / BIO-EMULSIFIERS FOR COMMERCIAL EXPLOITATION (MARISURF)

Start date: Sep 1, 2015, End date: Aug 31, 2020,

... develop (1) innovative approaches in discovering, characterizing and producing novel marine-derived bio-surfactants from a large bacterial collection (greater than 500 strains) housed at Heriot Watt University, originally isolated from various coastal and open ocean waters around the world, (2) novel, economic, and eco-friendly end-products with commercial applications in order to replace synthet ...
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 13

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Breast Cancer Risk after Diagnostic Gene Sequencing (BRIDGES) (BRIDGES)

Start date: Sep 1, 2015, End date: Aug 31, 2020,

Breast cancer affects more than 360,000 women per year in the EU and causes more than 90,000 deaths. Identification of women at high risk of the disease can lead to disease prevention through intensive screening, chemoprevention or prophylactic surgery. Breast cancer risk is determined by a combination of genetic and lifestyle risk factors. The advent of next generation sequencing has opened up th ...
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 20

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Virus-X: Viral Metagenomics for Innovation Value (Virus-X)

Start date: Apr 1, 2016, End date: Mar 31, 2020,

Biological sequence diversity in nowhere as apparent as in the vast sequence space of viral genomes. The Virus-X project will specifically explore the outer realms of this diversity by targeting the virosphere of selected microbial ecosystems and investigate the encoded functional variety of viral gene products. The project is driven by the expected large innovation value and unique properties of ...
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 15

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CellViewer: super-resolution systems microscopy to assess pluripotency and differentiation of stem cells at single cell level (CellViewer)

Start date: Feb 1, 2016, End date: Jan 31, 2020,

In this ambitious and multi-disciplinary proposal, we aim to develop new technologies that will allow us to visualize in single cells, in parallel and at the systems level, DNA, mRNAs and proteins with nanoscale resolution. We will refer to these novel technologies as the ‘CellViewer’: a unique cutting-edge high-throughput super-resolution (SR) microscopy approach (including new hardware and softw ...
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 6

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REsources from URban BIo-waSte (RES URBIS)

Start date: Jan 1, 2017, End date: Dec 31, 2019,

RES URBIS aims at making it possible to convert several types of urban bio-waste into valuable bio-based products, in an integrated single biowaste biorefinery and by using one main technology chain. This goal will be pursued through: - collection and analysis of data on urban bio-waste production and present management systems in four territorial clusters that have been selected in different cou ...
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 22

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MesopOrous matrices for localiZed pH-triggered releAse of theRapeuTic ions and drugs (MOZART)

Start date: Nov 1, 2015, End date: Oct 31, 2019,

The concept behind MOZART is to develop a library of inorganic nanomatrices to be used as smart platforms for effective, non-invasive and highly targeted therapies. MOZART will address, as proof of concept, nanomatrices to treat delayed bone healing and non-healing chronic skin wounds, which are both characterised by an inflammation and often infection. Mesoporous therapeutic glasses (MTGs), doped ...
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 11

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EU-CHINA Lever for IPM Demonstration (EUCLID)

Start date: Sep 15, 2015, End date: Sep 14, 2019,

More sustainable pest management methods are needed in order to reduce the negative effects of pesticides on human health and the environment. The overall goal of EUCLID is to contribute to secure the production of food for the increasing worldwide population while developing sustainable production approaches to be used in the European and Chinese agriculture.The choice of the crops of interest in ...
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 19

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Resource Efficient Food and dRink for the Entire Supply cHain (REFRESH)

Start date: Jul 1, 2015, End date: Jun 30, 2019,

The overall aim of the REFRESH project is to contribute significantly towards the objective of reducing food waste across the EU by 30% by 2025 (which amounts to between 25 to 40 million tonnes of food not being wasted in 2025[1], worth tens of billions of Euros a year) and maximizing the value from unavoidable food waste and packaging materials. To achieve this ambitious goal, we will adopt a sys ...
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 26

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Processing Underutilised Low value sugarbeet Pulp into VALUE added products (PULP2VALUE) (PULP2VALUE)

Start date: Jul 1, 2015, End date: Jun 30, 2019,

Sugar beet pulp (SBP) accounts for approx. 13 million tonnes in Europe and is a major residual stream from the sugar beet industry, which is currently valorised as low value feed and/or green gas. In order to increase the value of its side streams, PULP2VALUE developed multiple extraction techniques to isolate more valuable products from this large fraction of sugar beet pulp. Roughly 65% of the ...
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 7

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Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases (PRECISESADS)

Start date: Feb 1, 2014, End date: Jan 31, 2019,

We concur to the IMI on “Reclassification of SLE, connective tissue diseases and RA” call by presenting a proposal aimed at using the power of OMICs, and bioinformatics to identify new classifications for diseases known to share common pathophysiological mechanisms. Such knowledge has not been applied to individual patients, depriving them from potential benefits in terms of the use of new therape ...
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 30

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EnviGuard – Development of a biosensor technology for environmental monitoring and disease prevention in aquaculture ensuring food safety (EnviGuard)

Start date: Dec 1, 2013, End date: Nov 30, 2018,

The objective of the EnviGuard project is to develop a highly specific and precise (i.e. quantitative and qualitative) in situ measurement device for currently hard to measure man-made chemical contaminants and biohazards (toxic microalgae, viruses & bacteria, biotoxins & PCBs) that can be used as an early warning system in aquaculture and as an environmental monitor to assess the good environment ...
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 19

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Piezoelectronic Transduction Memory Device (PETMEM)

Start date: Dec 1, 2015, End date: Nov 30, 2018,

Computer clock speeds have not increased since 2003, creating a challenge to invent a successor to CMOS technology able to resume performance improvement. The key requirements for a viable alternative are scalability to nanoscale dimensions – following Moore’s Law – and simultaneous reduction of line voltage in order to limit switching power. Achieving these two aims for both transistors and memor ...
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 11

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Global material flows and demand-supply forecasting for mineral strategies (MinFuture)

Start date: Dec 1, 2016, End date: Nov 30, 2018,

Global demand for minerals is growing rapidly, driven by rapid population growth, urbanisation and an increasingly diverse range of technical applications. Global material supply chains linking the extraction, transport and processing stages of raw materials have become increasingly complex and today involve multiple players and product components. An interactive platform that provides transparenc ...
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 16

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An integrated approach to diversify the genetic base, improve stress resistance, agronomic management and nutritional/processing quality of minor cereal crops for human nutrition in Europe (HealthyMinorCereals)

Start date: Sep 1, 2013, End date: Aug 31, 2018,

Consumers have increasing demands for healthy, nutritious, and innovative food produced sustainably. Minor cereals can address these points, as well as contributing to feed and non-food markets. However, they have been hardly developed as commercial varieties, with no major investment to exploit genetic diversity in breeding programmes, and have low yields. There has been little research to optimi ...
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 16

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Capture, dissemination and analysis of multiscale cell migration data for biological and clinical applications (MULTIMOT) (MULTIMOT)

Start date: Aug 1, 2015, End date: Jul 31, 2018,

This proposal addresses the call topic ‘Advancing bioinformatics to meet biomedical and clinical needs’ (PHC-32-2014), with the focus on the standardization, dissemination and meta-analysis of cell migration data. Cell migration is the fundamental process in medically highly relevant topics, including morphogenesis, immune function, wound healing, and cancer metastasis, and the study of cell migra ...
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 10

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Enabling Robot and assisted living environment for Independent Care and Health Monitoring of the Elderly (ENRICHME)

Start date: Mar 1, 2015, End date: Feb 28, 2018,

ENRICHME tackles the progressive decline of cognitive capacity in the ageing population proposing an integrated platform for Ambient Assisted Living (AAL) with a mobile service robot for long-term human monitoring and interaction, which helps the elderly to remain independent and active for longer. The system will contribute and build on recent advances in mobile service robotics and AAL, exploiti ...
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 12

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Synergistic Fouling Control Technologies (SEAFRONT)

Start date: Jan 1, 2014, End date: Dec 31, 2017,

Marine biofouling, the unwanted colonization of marine organisms on surfaces immersed in seawater has a huge economic and environmental impact in terms of maintenance requirements for marine structures, increased vessel fuel consumption, operating costs, greenhouse gas emissions and spread of non-indigenous species. The SEAFRONT project will aim to significantly advance the control of biofouling a ...
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 19

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Synthetic Cellular Signaling Circuits (SynSignal)

Start date: Nov 1, 2013, End date: Oct 31, 2017,

Cellular signaling systems are crucially important for a broad range of critical health and disease areas and high value industrial applications. Signaling systems are the target for more than half of the medicines marketed by the pharmaceutical industry, and form the main R&D area for the nutrition, flavour and fragrance industries. SynSignal is a multidisciplinary high-tech consortium working in ...
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 10

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Glycerol Biorefinery Approach for the Production of High Quality Products of Industrial Value (GRAIL)

Start date: Nov 1, 2013, End date: Oct 31, 2017,

The project GRAIL has been build with 15 partners from 9 different countries with the aim of finalising the solutions given previously to the valorization of glycerol and transform then in valuable products in a biorefinery approachThe overall concept of GRAIL project is the use, exploitation and further development of the state of the art in the field of bio-based products from glycerol and the d ...
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 16

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NanoBioEngineering of BioInspired BioPolymers (Nano3Bio)

Start date: Oct 1, 2013, End date: Sep 30, 2017,

The Nano3Bio project convenes a consortium of world renowned experts from 8 EU universities, 1 large company, and 14 SME, to develop biotechnological production systems for nanoformulated chitosans. Chitosans, chitin-derived polysaccharides varying in their degree of polymerisation (DP), degree of acetylation (DA), and pattern of acetylation (PA), are among the most versatile and most promising bi ...
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 23

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Developing a validated technology platform for the application of oxygen dependent enzymes in synthesis and transformation of alcohols (BIOOX)

Start date: Oct 1, 2013, End date: Sep 30, 2017,

Currently the aerobic bio-catalytic oxidation reaction is the one that would have the biggest impact on the future uptake of industrial biotechnology in Europe. Chemical oxidation is both hazardous and has high environment impacts. Many oxidative bio-catalytic reactions and transformations have been identified in academic laboratories but only a very small number have been applied by industry to o ...
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 12

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Integrated European –omics research project for diagnosis and therapy in rare neuromuscular and neurodegenerative diseases (Neuromics)

Start date: Oct 1, 2012, End date: Sep 30, 2017,

Neurodegenerative (ND) and neuromuscular (NM) disease is one of the most frequent classes of rare diseases, affecting life and mobility of 500,000 patients in Europe and millions of their caregivers, family members and employers. This NEUROMICS project brings together the leading research groups in Europe, five highly innovative SMEs and relevant oversea experts using the most sophisticated Omics ...
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 20

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NUTRIENTS AND REGENERATED WATER RECYCLING IN WWTPs THROUGH TWIN-LAYER MICROALGAE CULTURE FOR BIOFERTILIZERS PRODUCTION (LIFE+ TL-BIOFER)

Start date: Jul 1, 2014, End date: Jun 30, 2017,

Background Human activities can have a significant negative impact on the environment, particularly by affecting the global biogeochemical cycles of carbon, nitrogen and phosphorus. Water supplies to urban areas and subsequent sanitation and wastewater systems – even when conventional treatment occurs –produce enormous punctual loadings (point sources ...
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 4

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Network for Development of Soft Nanofibrous Construct for Cellular Therapy of Degenerative Skeletal Disorders (FIBROGELNET)

Start date: Jan 1, 2013, End date: Jun 30, 2017,

"High incidence of degenerative skeletal tissue disorders in a progressively aging human population make tissue engineering of cartilage and bone a focus of extensive research. Bone and joint disorders are the most common disease in Europe: more than 100 million European citizens suffer from arthritis and 19 million people have osteoporosis (one of three women and one of eight men are affected). T ...
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 7

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A stepping stone approach towards the Genetics Clinic of the Future (GCOF)

Start date: Jan 1, 2015, End date: Jun 30, 2017,

The Genetics Clinic of the Future (GCOF) project aims to ensure that the clinical implementation of genome technologies is relevant and responsive to the needs of all. It offers a stepping stone approach towards the genetics clinic of the future, engaging all stakeholders involved in a process of mutual learning and information exchange. The GCOF project implements key Science with and for Society ...
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 13

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OPERATIONALISATION OF NATURAL CAPITAL AND ECOSYSTEM SERVICES: FROM CONCEPTS TO REAL-WORLD APPLICATIONS (OPENNESS)

Start date: Dec 1, 2012, End date: May 31, 2017,

Despite improved understanding of the links between ecosystem health, provision of ecosystem services and human well-being, further conceptual and empirical work is needed to make the ideas of ecosystem services (ESS) and natural capital (NC) operational. OpenNESS will therefore develop innovative and practical ways of applying them in land, water and urban management: it will identify how, where ...
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 39

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High value-added chemicals and BIoreSIns from alGae biorefineries produced from CO2 provided by industrial emissions (BISIGODOS)

Start date: Nov 1, 2013, End date: Apr 30, 2017,

BISIGODOS aims to address the production of valuable algae derived chemicals, amino acids and high added-value bio-resins for coatings, printing, food and hair care and adhesives applications, starting from algae biomass fed directly with CO2 from industrial emissions (cement, steel factory, thermal power plants, etc.) as a raw material that is cost-effective and renewable. The process is assisted ...
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 18

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European Autism Interventions - A Multicentre Study for Developing New Medications (EU-AIMS)

Start date: Apr 1, 2012, End date: Mar 31, 2017,

Despite dramatic advances in molecular and imaging technologies, there are currently no effective pharmacological treatments for the core symptoms of autism spectrum disorder (ASD). Major obstructions to this include a lack of aetiologically-driven or pathophysiologically-accurate animal models; an absence of tests that indicate efficacy; and reliance of clinical trials on DSM/ICD10 categories wh ...
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 29

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Resistance in Gram-Negative Organisms: Studying Intervention Strategies (R-GNOSIS)

Start date: Oct 1, 2011, End date: Mar 31, 2017,

Antibiotics are a mainstay of public health, but their use has increased exponentially leading to the emergence of antibiotic resistance. The R-GNOSIS (Resistance in Gram-Negative Organisms: Studying Intervention Strategies) project combines 5 international clinical studies, all supported by highly innovative microbiology, mathematical modelling and data-management, to determine - in the most rele ...
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 27

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Critical Infrastructure Preparedness and Resilience Research Network (CIPRNet)

Start date: Mar 1, 2013, End date: Feb 28, 2017,

The Critical Infrastructure Preparedness and Resilience Research Network or CIPRNet establishes a Network of Excellence in Critical Infrastructure Protection (CIP) R&D for a wide range of stakeholders including (multi)national emergency management, critical infrastructure (CI) operators, policy makers, and the society.CIPRNet builds a long-lasting, durable virtual centre of shared and integrated k ...
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 12

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Mechanism-Based Integrated Systems for the Prediction of Drug-Induced Liver Injury (MIP-DILI)

Start date: Feb 1, 2012, End date: Jan 31, 2017,

The current test systems employed by Industry are poorly predictive for Drug induced liver injury (DILI). The ‘MIP-DILI’ project will address this situation by the development of innovative preclinical test systems which are both mechanism-based and of physiological, pharmacological and pathological relevance to DILI in humans. An iterative, tiered approach with respect to test compounds, test sys ...
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 29

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Thoroughly Optimised Production Chassis for Advanced Pharmaceutical Ingredients (TOPCAPI)

End date: Jan 1, 2017,

TOPCAPI will exploit the natural fabrication power of actinomycetes as microbial cell factories to produce three high value compounds: GE2270, a starter compound for the semi-synthesis of NAI-Acne, a new topical anti-acne drug in Phase II clinical trials; 6-desmethyl-tetracycline (6DM-TC) and 6-desmethyl 6-deshydro tetracycline (6DM6DH-TC), intermediates for semi-synthetic conversion to medically ...
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 8

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Sustainable Technologies for Calcined Industrial Minerals in Europe (STOICISM)

Start date: Jan 1, 2013, End date: Dec 31, 2016,

Europe is a major global producer of industrial minerals. Around 180 million tonnes per year of products are extracted in the EU, with an estimated contribution of €10 billion to European GDP and offering direct employment to some 42,500 people. A secure supply of sustainable mineral products is essential to maintaining the European mining, mineral and manufacturing industries.The main objective ...
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 17

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Microwave Nanotechnology for Semiconductor and Life Sciences (NANOMICROWAVE)

Start date: Jan 1, 2013, End date: Dec 31, 2016,

Current applications of microwave technologies in communications, remote sensing and in industry are based on the properties of the interaction of microwaves with matter at supra-wave length scales (above centimetres). The developments performed in Nanotechnology in recent years makes now conceivable to explore the interaction of microwaves with matter at much smaller scales, from micrometres to n ...
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 10

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Developing a global understanding of the PRC and NuRD complexes in stem cell differentiation, in health and disease (4DCELLFATE)

Start date: Dec 1, 2011, End date: Nov 30, 2016,

Embryonic stem (ES) cells have the potential to differentiate into any type of cell as well as to renew indefinitely in culture. They hold great potential for the development of personalized medicines. However, the molecular mechanisms underpinning cell fate decisions by individual cells are poorly understood. There is compelling evidence that two large multi-protein machines, the Nucleosome Remod ...
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 13

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Biopharmaceutical therapy for treatment of Primary Hyperoxaluria (ELIMOX)

Start date: Oct 1, 2013, End date: Sep 30, 2016,

"Interest in the use of naturally occurring human gut bacteria as pharmaceutical drugs has increased as knowledge about the human microbiota and its role in health and disease has advanced.The ELIMOX project proposes to develop a new drug from Oxalobacter formigenes, an anaerobic bacterium whose only carbon source is oxalate, for the treatment of primary hyperoxaluria (PH). PH is a rare and life-t ...
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 12

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Dietary Fibers supporting Gut and Immune Function - From polysaccharide compound to health claim (FIBEBIOTICS)

Start date: Jan 1, 2012, End date: Jun 30, 2016,

The project goal is to support the development of functional food ingredients and products that are beneficial for the human gut & immune system and therefore of crucial importance for quality of life. The project will study the effects of specific non-digestible polysaccharides which have shown health potential in this field. The health effects of NPS will be focused around enhancing immune defen ...
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 17