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2 European Projects Found

Searched on 125080 European Projects

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Single-Cell Epigenetics in Cell Fate Determination (CELL FATE)

Start date: Jan 1, 2015, End date: Dec 31, 2017,

The demonstration of induced pluripotency and direct lineage conversion of cells has led to remarkable insights regarding the roles of epigenetic modifications in mediating cell state transitions. However, approaches to elucidate the molecular mechanisms behind induced reprogramming are hindered by the inefficiency of induction and the interplay of reprogramming mechanisms with other cellular proc ...
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Visualizing the molecular control of blood - stroma interactions at the single cell level (VB-SINT)

Start date: Nov 1, 2007, End date: May 31, 2009,

The behaviour of hematopoietic cells is influenced by their microenvironment. These "niches" are composed of variety of cells, including stromal cells. As cells mature, they move from one niche to another within the bone marrow until they are released into the periphery. To further understand these interactions, we will utilize a novel, non-invasive computer-driven microscopy program to visualize ...
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