Search for European Projects

7 European Projects Found

Searched on 125080 European Projects

 FINISHED 

ATMP GMP Open Access Research Alliance - AGORA (AGORA)

Start date: Sep 1, 2013, End date: Oct 31, 2015,

We propose an academic & industrial partnership to facilitate safe and effective delivery of new advanced therapy medicines within the framework of the relevant EU regulations which our previous FP7 funded project have identified as creating unanticipated barriers to development of this field. Over 80% of advanced therapy medicines (ATMPs) trials in the EU are academic investigator led and sponsor ...
Read Project

 8

 FINISHED 

Novel immunotherapies for type 1 diabetes (NAIMIT)

Start date: Nov 1, 2009, End date: Apr 30, 2015,

This proposal will pioneer the concept of tailored interventions with minimal immune system interference in new onset T1DM, leading to beta-cell protection and restoration, based on a solid understanding of the disease pathogenesis. This will enable experimental findings to be adopted for future clinical application. Four work packages are grouped around ‘Reversal of autoimmunity’, in which two ke ...
Read Project

 15

 FINISHED 

Molecular regulation of blood coagulation factor V: from snakes to humans (MoReFV)

Start date: Sep 1, 2010, End date: Aug 31, 2014,

The overall goal of this proposal is to provide new information on the molecular mechanisms that regulate the cofactor function of blood coagulation factor V (FV). Shedding light on these processes may provide a framework for developing novel strategies for prevention and treatment in cases of disregulation of the blood coagulation response. This is a uniquely complex process that protects organis ...
Read Project

 1

 FINISHED 

Identification of Mechanisms Correlating with Susceptibility for Avian Influenza (IMECS)

Start date: Apr 1, 2008, End date: Dec 31, 2012,

IMECS is a proposal of the FLUSECURE network aimed at combating the threat of new and re-emerging forms of highly pathogenic influenza in its first stages of a disease by identifying mechanisms of protection that are essential for a solid immune response to avian influenza. IMECS is uniquely featured by correlating research in humans directly to protection from influenza. The IMECS initiative was ...
Read Project

 8

 FINISHED 

Dissection of T cell cosignaling and development of vaccination strategies to cytomegalovirus (Vaccination to CMV)

Start date: Oct 1, 2010, End date: Sep 30, 2012,

Cytomegalovirus (CMV, a β-herpesvirus) infects the majority of the world’s population, establishing a lifelong infection. This infection is largely asymptomatic in immune competent hosts, but causes severe disease in immunocompromised neonates and adults. In healthy persistently infected individuals huge numbers of CMV-specific T cells accumulate over time (i.e. “memory inflation”), a process rece ...
Read Project

 1

 FINISHED 

Set up and comparison of multiple stem cell approaches for kidney repair (STAR-T REK)

Start date: Nov 1, 2008, End date: Oct 31, 2011,

"With the increasing rate of end-stage renal failure and limited alternatives for its treatment, potential regenerative approaches for kidney damages are urgently needed. Because of the complexity of the organ, the development of stem cell therapies for kidney is still in its infancy. Identifying which cell types are capable of beneficial effects is the critical step required to realize the potent ...
Read Project

 11

 FINISHED 

Stem Cell Expansion - Expansion and engraftment of haematopoietic and mesenchymal stem cells (STEMEXPAND)

Start date: Nov 1, 2008, End date: Oct 31, 2011,

"Serious disorders of the blood system, particularly malignant blood disorders and genetic diseases can be effectively treated by blood and marrow transplantation. Despite considerable success with this treatment modality during the last decades, lack of suitable donors, engraftment failure and graft versus host disease remain serious problems that need to be addressed. This project aims to addres ...
Read Project

 8