Search for European Projects

17 European Projects Found

Searched on 125080 European Projects

 ONGOING 

DARIAH ERIC Sustainability Refined (DESIR)

Start date: Jan 1, 2017, End date: Dec 31, 2019,

Europe has a long and rich tradition as a centre for the arts and humanities. However, the digital transformation poses challenges to the arts and humanities research landscape all over the world. Responding to these challenges the Digital Research Infrastructure for Arts and Humanities (DARIAH) was launched as a pan-European network and research infrastructure. After expansion and consolidation, ...
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 18

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... the most complex and heterogeneous datasets that science can currently imagine, with unprecedented volumes of biological data to manage.Data will only generate long-term value if it is Findable, Accessible, Interoperable and Re-usable (FAIR). This requires a scalable infrastructure that connects local, national and European efforts and provides standards, tools and training for data stewardship.Fo ...
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 47

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In the coming decade a significant number of the 500.000.000 European (EU/EEA) citizens will have their genome determined routinely. This will be complemented with much cheaper (currently ~20 Euro per measurement) acquisition of the metabolome of biofluids (e.g. urine, saliva, blood plasma) which will link the genotype with metabolome data that captures the highly dynamic phenome and exposome of p ...
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 17

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SYSTEMS GLYCOBIOLOGY OF GASTRIC CANCER (GASTRICGLYCOEXPLORER)

Start date: May 1, 2013, End date: Apr 30, 2018,

This ITN is built around the biological question of O-glycosylation in gastric cancer for training in systems glycobiology. For meeting the needs of the research goal and for training for future systems glycobiology operations, cross disciplinary international institutes have been identified with top level state-of-the-art glycobioanalytical, glycotechnological and glycobioinformatics platforms. T ...
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 13

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Human Brain Project Specific Grant Agreement 1 (HBP SGA1)

Start date: Apr 1, 2016, End date: Mar 31, 2018,

Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses I ...
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 126

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... established cardiovascular disease (CVD) animal models and patient cohorts. The coordinated application of these tools and know-how will identify pathophysiological mechanisms and key molecules responsible for onset and progression of CVD and validate their potential to serve as molecular targets for therapeutic intervention. To this end, the consortium will also use unique resources to evaluate m ...
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 19

 FINISHED 

SYSTEMS BIOLOGY OF PATHWAYS INVOLVING BRAIN AGEING (AGEDBRAINSYSBIO)

Start date: Jan 1, 2013, End date: Dec 31, 2016,

... ng in subregion of a neuron (such as dendrites and dendritic spines), (3) the inclusion of these experimentally validated networks in larger networks obtained from available databases to extend possible protein interactions, (4) the identification of human and/or primate positive selection either in coding or in regulatory gene sequences,(5) the manipulation of these human and/or primate acceler ...
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 15

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The Open Pharmacological Concepts Triple Store (OPEN PHACTS)

Start date: Mar 1, 2011, End date: Feb 29, 2016,

... and chemogenomics will be developed creating a comprehensive Systems Chemical Biology Analysis Network. Security issues around proprietary data, shared via the Open PHACTS Discovery Platform and accessible for safe querying and reasoning will be properly addressed with expert trusted parties.The Open PHACTS consortium comprises 20 European academic and SME partners, with leading experts in the fie ...
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 32

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Pancreatic ductal adenocarcinoma (PDAC) causes 34000 deaths in the EU every year. Conventional cancer treatments have close to no impact on this disease. As a result, almost all patients diagnosed with PDAC develop metastases and eventually die. Given this poor outlook, the search for new therapeutics is mandatory. These will have to target relevant cancer pathways and be designed based on the ava ...
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 12

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An absolute or relative loss of beta-cell mass and function underlie the development of type I and type 2 diabetes.Preventing beta-cell demise or restoring their number and function is a major therapeutic goal. However,development of novel diagnostic and prognostic tools, and of novel therapeutic modalities, is hampered by the limited knowledge of the molecular pathways that control beta-cell demi ...
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 23

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Effective and long term treatment of cancer is now in sight, but will ultimately require an increasingly ‘personalised’ approach where the ‘right’ combination of drugs will be administered to the ‘right’ patients, based on a detailed understanding of their genetic background and their co-associated sensitivity or resistance ‘biomarkers’. Efforts are specifically required to identify validated risk ...
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 11

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The main aim of AllBio will be the coordination of the partner's activities that are aimed at the extension of a large number of bioinformatics facilities towards applicability in target life science areas beyond human health. Bioinformatics facilities developed for the human health area will be extensively tested on unicellular (incl. bacterial), plant and (farm) animal genomes, and they will be ...
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 11

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... ngle point of data submission to the user; (ii) to ensure data availability in all of the different member databases; (iii) to use community standard formats to represent the data, so it becomes accessible to all regardless of data origin; (iv) to provide added value through different views on the same data, from repositories to derived search tools.With an international consortium and support fro ...
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 13

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... ctly into the flow of newly sequenced genomes, will allow a qualitative increase in the speed and reliability of the pathway generation process. Pathways and models produced the pipeline will be accessible to the scientific community as an integrated resource via the Microme portal. Finally, taking advantage of the availability of pathway assemblies from a large sample of genomes, methods for comp ...
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 16

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The aim of the PSIMEx proposal is to systematically make published molecular interaction data computationally accessible. We plan to further develop the existing standard for molecular interactions developed by the HUPO Proteomics Standards Initiative, and to promote its implementation in the entire chain from experiment planning via data formatting and analysis to data representation in journal p ...
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 15

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Genotype-To-Phenotype Databases: A Holistic Solution (GEN2PHEN)

Start date: Jan 1, 2008, End date: Jun 30, 2013,

"The GEN2PHEN project aims to unify human and model organism genetic variation databases towards increasingly holistic views into Genotype-To-Phenotype (G2P) data, and to link this system into other biomedical knowledge sources via genome browser functionality. The project will establish the technological building-blocks needed for the evolution of today’s diverse G2P databases into a future seaml ...
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 23

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... will include:A Holding stakeholder meetings to bring together national representatives, key scientific opinion and funding organisations.B Establishing working parties, supported by technical feasibility studies where appropriate, to address the tasks and issues above with final reports at month 18.C Consolidating these reports into a management and funding proposal to be sent to member states an ...
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