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Molecular mechanisms underlying BDNF functions in the brain: role of ARMS protein (Neurotrophins-ARMS)
Start date: Jan 1, 2008, End date: Dec 31, 2011,
Neurotrophins are growth factors including NGF, BDNF, NT-3 and NT-4, which function in cell survival, differentiation, apoptosis, axonal and dendritic growth, and plasticity in the nervous system. Additionally, BDNF has been implicated in human brain pathologies, such as depression, Alzheimer, Huntington, Parkinson, etc. Neurotrophins bind to two different sets of receptors, Trk and p75 receptors, ...
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