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Over 40 European Projects Found

Searched on 125080 European Projects

 FINISHED 

A Systems medicine approach to chronic inflammatory disease (SYSCID)

Start date: Jan 1, 2017, End date: Mar 31, 2022,

"The SYSCID consortium aims to develop a systems medicine approach for disease prediction in CID. We will focus on three major CID indications with distinct characteristics, yet a large overlap of their molecular risk map: inflammatory bowel disease, systemic lupus erythematodes and rheumatoid arthritis. We have joined 15 partners from major cohorts and initiatives in Europe (e.g.IHEC, ICGC, Twins ...
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 16

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Particle-Surface Interactions in Near Field Optics: Spin-orbit Effects of Light and Optical/Casimir Forces (PSINFONI)

Start date: Mar 1, 2017, End date: Feb 28, 2022,

PSINFONI aims to open new avenues of research in ultrafast routing and polarization synthesis of light in nanophotonics, and in the manipulation, sorting, levitation and trapping of nanoparticles, molecules, or single atoms near novel nanomaterial surfaces. To this end, we will explore the fundamentals and applications of a range of novel nanophotonic phenomena: (i) spin-orbit interactions of ligh ...
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 1

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Mechanical control of biological function (MECHANO-CONTROL)

Start date: Jan 1, 2017, End date: Dec 31, 2021,

Mechanical forces transmitted through specific molecular bonds drive biological function, and their understanding and control hold an uncharted potential in oncology, regenerative medicine and biomaterial design. However, this potential has not been realised, because it requires developing and integrating disparate technologies to measure and manipulate mechanical and adhesive properties from the ...
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 7

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Authority and Innovation in Early Franciscan Thought (c. 1220-56) (INNOVATION)

Start date: Jan 1, 2017, End date: Dec 31, 2021,

...assumption by producing the first comprehensive study of the sources, method, content, and later medieval reception of early Franciscan thought. In conducting this study, I will implement a groundbreaking method of reading scholastic texts, which is attentive to the way that practice informed theory in the high Middle Ages. This ‘practice-led’ hermeneutic will provide a resource for re-envisaging ...
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 2

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Brain network based stratification of mental illness (STRATIFY)

Start date: Oct 1, 2016, End date: Sep 30, 2021,

To reduce the burden of mental disorders it is a formidable aim to identify widely applicable disease markers based on neural processes, which predict psychopathology and allow for targeted interventions. We will generate a neurobehavioural framework for stratification of psychopathology by characterising links between network properties of brain function and structure and reinforcement–related be ...
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 4

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Mitochondrial DNA degradation and sterile inflammation in the heart (RAMBO)

Start date: Sep 1, 2016, End date: Aug 31, 2021,

Heart failure is the leading cause of morbidity and mortality in developed countries including EU. Novel and efficient therapeutics to treat patient with heart failure have to be developed. Mitochondria are subcellular organelles that produce energy and dynamic organelles that fuse and divide. Dysregulated mitochondrial activity results in generation of free radicals which cause damage to cellular ...
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Higgs bundles: Supersymmetric Gauge Theories and Geometry (HIGGSBNDL)

Start date: Sep 1, 2016, End date: Aug 31, 2021,

String theory provides a unified description of particle physics and gravity, within a consistent theory of quantum gravity. The goal of this research is to develop both the phenomenological implications as well as conceptual foundations of string theory and its non-perturbative completions, M- and F-theory. Both, seemingly independent, questions are deeply connected to a mathematical structure, t ...
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 2

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Quantum Black Holes: A macroscopic window into the microstructure of gravity (QBH)

Start date: Sep 1, 2016, End date: Aug 31, 2021,

The thermodynamic behavior of black holes is a precious clue in unravelling the microscopic structure of quantum gravity.High precision computations of quantum black hole entropy provide a new window into the fundamental microscopic theory of gravity and its deviations from classical general relativity. Traditional methods of quantum field theory have proved to be not well-suited to perform these ...
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 1

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Dissecting the cellular mechanics of contact inhibition of locomotion (CIL2015)

Start date: Sep 1, 2016, End date: Aug 31, 2021,

Our aim is to dissect the mechanisms of contact inhibition of locomotion (CIL), a process whereby migrating cells collide and repel each other, as it is now clear that CIL is pivotal to understanding embryogenesis and pathologies such as cancer. We have developed an in vivo model using Drosophila macrophages (hemocytes), along with novel analytical tools, to examine the contact inhibition response ...
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 1

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Towards Early Molecular Diagnostics of Schizophrenia (SZ_TEST)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

...iderable socioeconomic burden. In general, the chronic nature and the high degree of patient disability make SZ the fourth leading cause of disease burden across the globe with the management costs making up ~3% of the total healthcare budget in the Western countries. The situation is even direr in some regions, including northern Sweden and Finland, where relative prevalence of SZ exceeds two to ...
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 9

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Comorbid Conditions of Attention deficit / hyperactivity disorder (CoCA)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

Understanding mechanisms underlying comorbid disorders poses a challenge for developing precision medicine tools. Psychiatric disorders are highly comorbid, and are among the last areas of medicine, where classification is driven by phenomenology rather than pathophysiology. We will study comorbidity between the most frequent psychiatric conditions, ADHD, mood/anxiety, and substance use disorders, ...
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 17

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Liaison in Scientific Training for European auditory Neuroscience (LISTEN)

Start date: Dec 1, 2016, End date: Nov 30, 2020,

This ITN will train 10 ESRs to meet the urgent need for translation of Auditory Neuroscience into commercial and pharmaceutical products to treat hearing disorders including tinnitus. Tinnitus is the debilitating perception of imaginary sound that is often associated with hearing loss. This Liaison in Scientific Training for European auditory Neuroscience (LISTEN) is a consortium of top hearing sc ...
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 9

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Common mechanisms and pathways in Stroke and Alzheimer's disease. (CoSTREAM)

Start date: Dec 1, 2015, End date: Nov 30, 2020,

... AD, or both. Another important concept is that mechanisms under study will not only include the known pathways of ischemic vasculopathy and CAA, but we will explore and unravel novel mechanisms linking stroke and AD. We will do so by exploiting our vast international network in order to link various big datasets and by incorporating novel analytical strategies with emerging technologies in the fi ...
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 11

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European AIDS Vaccine Initiative 2020 (EAVI2020)

Start date: Nov 1, 2015, End date: Oct 31, 2020,

HIV-1 is responsible for a global pandemic of 35 million people, and continues to spread at a rate of >2 million new infections/year. It is widely acknowledged that a protective vaccine would be the most effective means to reduce HIV-1 spread and ultimately eliminate the pandemic, while a therapeutic vaccine may help mitigate the clinical course of disease and lead to strategies of viral eradicati ...
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 27

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The values of French language and literature in the European Middle Ages (TVOF)

Start date: Sep 1, 2015, End date: Aug 31, 2020,

Two questions about linguistic identity lie at the heart of this project. What is the relation historically between language and identity in Europe? How are cognate languages demarcated from each other? Normative models of national languages helped shape Europe. Yet they did not become hegemonic until the 19th century. Indeed, they were imposed (not always successfully) on a linguistic map of Euro ...
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 1

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Dark Matter and the Early Universe in the LHC Era (DARKHORIZONS)

Start date: Sep 1, 2015, End date: Aug 31, 2020,

The discovery of a Higgs like particle in its first science run shows that we are truly in the LHC era and when collisions resume we will learn more about the physics of the TeV scale. There are two main areas at the interface of particle physics and cosmology that the LHC will shed light on - If dark matter is a thermal relic then we naturally expect new particle physics close to this TeV energy ...
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 1

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REACH: Risk, Resilience, Ethnicity and AdolesCent Mental Health (REACH)

Start date: Sep 1, 2015, End date: Aug 31, 2020,

The overarching aim of REACH is to examine groundbreaking questions on the developmental origins of psychosis in migrant and minority ethnic populations using a highly innovative accelerated cohort study of adolescents, to be conducted in south London (UK). It has been known for over 50 years that the incidence of psychotic disorders is high in many migrant and minority ethnic groups across many c ...
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 1

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Ageing Trajectories of Health: Longitudinal Opportunities and Synergies (ATHLOS)

Start date: May 1, 2015, End date: Apr 30, 2020,

The objective of the ATHLOS Project is to achieve a better understanding of ageing by identifying patterns of healthy ageing pathways or trajectories, the determinants of those patterns, the critical points in time when changes in trajectories are produced, and to propose timely clinical and public health interventions to optimise healthy ageing. Moreover, a new definition of ‘old age’ based on ma ...
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 15

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Translating neuroimaging findings from research into clinical practice (PSYSCAN)

Start date: Feb 1, 2014, End date: Jan 31, 2020,

Abstract 9Neuroimaging (NI) has enormous potential to improve the clinical care of patients with psychiatric disorders, but has yet to deliver. The PSYSCAN project will address this issue directly by developing a NI-based tool that will help clinicians resolve key clinical issues in the management of patients with psychotic disorders. Clinicians will use the tool to assess patients with a standard ...
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 24

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Intelligent Parkinson eaRly detectiOn Guiding NOvel Supportive InterventionS (i-PROGNOSIS)

Start date: Feb 1, 2016, End date: Jan 31, 2020,

Transition from healthy status to Parkinson’s Disease (PD) is vaguely tractable, since symptoms can be so subtle in the early stages that they go unnoticed. Lack of biomarkers and/or findings on routine MRI and CT scans, PD is left undiagnosed for years, gradually affecting the life of over 6.5 million of older adults (>55-60 yrs) worldwide, increasing the risk of their health deterioration. Epide ...
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 11

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DARIAH ERIC Sustainability Refined (DESIR)

Start date: Jan 1, 2017, End date: Dec 31, 2019,

Europe has a long and rich tradition as a centre for the arts and humanities. However, the digital transformation poses challenges to the arts and humanities research landscape all over the world. Responding to these challenges the Digital Research Infrastructure for Arts and Humanities (DARIAH) was launched as a pan-European network and research infrastructure. After expansion and consolidation, ...
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 18

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Imaging the Force of Cancer (FORCE)

Start date: Jan 1, 2016, End date: Dec 31, 2019,

Cancer is the second leading cause of mortality in EU member states with ~90% of all cancer deaths caused by metastatic spread. Despite its significance, measuring metastatic potential as well as potential indicators of therapy efficacy remain unmet clinical challenges. Recently, it has been demonstrated in vitro, that aggressive metastatic cells pull on their surroundings suggesting that metastat ...
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PROMOTING MENTAL WELLBEING IN THE AGEING URBAN POPULATION: DETERMINANTS, POLICIES AND INTERVENTIONS IN EUROPEAN CITIES (MINDMAP)

Start date: Jan 1, 2016, End date: Dec 31, 2019,

Major depressive disorder, dementia, anxiety disorders, and substance abuse affect a substantial part of the European older population. Over 70% of Europeans reside in cities, and this percentage will increase in the next decades. Urbanization and ageing have enormous implications for public mental health. Cities pose major challenges for older citizens, but also offer opportunities for the design ...
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 14

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In Vivo Spectral Photon Counting CT Molecular Imaging in Cardio- and Neuro-Vascular Diseases (SPCCT)

Start date: Jan 1, 2016, End date: Dec 31, 2019,

The objective of the SPCCT project is to develop and validate a widely accessible, new quantitative and analytical in vivo imaging technology combining Spectral Photon Counting CT and contrast agents, to accurately and early detect, characterize and monitor neurovascular and cardiovascular disease. Spectral Photon Counting Computed Tomography (SPCCT) is a new imaging modality, currently in develop ...
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 12

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NAture Insurance value: Assessment and Demonstration (NAIAD)

Start date: Dec 1, 2016, End date: Nov 30, 2019,

...vices by (i) enabling full operationalisation through improved understanding of ecosystem functionality and its insurance value at a broad range of scales in both urban and rural context; (ii) making explicit the links between ecosystem values and social risk perception; and (iii) the application of developed methods and tools in water management by relevant stakeholders, especially businesses, pu ...
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SoBigData Research Infrastructure (SoBigData)

Start date: Sep 1, 2015, End date: Aug 31, 2019,

...n the existing clusters of excellence in social data mining research, but also create a pan-European, inter-disciplinary community of social data scientists, fostered by extensive training, networking, and innovation activities. In addition, as an open research infrastucture, SoBigData will promote repeatable and open science.Although SoBigData is primarily aimed at serving the needs of researcher ...
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 12

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Integrating Technology into Mental Health Care Delivery in Europe (ICare)

Start date: Sep 1, 2015, End date: Aug 31, 2019,

The evidence base of Internet-based interventions in the prevention and treatment of mental health conditions has rapidly grown in the past decade. Yet many European countries (e.g., Germany, Austria, Switzerland, Great Britain, The Netherlands, Spain) have not implemented these promising approaches into health systems. Individuals with risk conditions or distinct mental health problems interested ...
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 13

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The Developing Human Connectome Project (dHCP)

Start date: Sep 1, 2013, End date: Aug 31, 2019,

...actable neuropsychiatric diseases.The connectome can be studied at millimetre scale in humans by neuroimaging, particularly diffusion and functional connectivity Magnetic Resonance Imaging. By linking imaging data to genetic, cognitive and environmental information it will be possible to answer previously unsolvable questions concerning normal mental functioning and intractable neuropsychiatric di ...
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 4

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Efficacy and safety of low-dose IL-2 (ld-IL-2) as a Treg enhancer for anti-neuroinflammatory therapy in newly diagnosed Amyotrophic Lateral Sclerosis (ALS) patients (MIROCALS)

Start date: Sep 1, 2015, End date: Aug 31, 2019,

Amyotrophic Lateral Sclerosis (ALS) is a fatal degenerative disorder of the brain and spinal cord affecting some 40,000 individuals in Europe, causing 11,000 deaths each year. Our pioneering work on riluzole showed that it is possible to modify ALS progression but all subsequent trials of potential neuroprotective agents have failed. Thus, drug development in ALS, including trial design, patient s ...
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 12

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Cortical circuit assembly in the developing mouse neocortex (CorCir)

Start date: Aug 15, 2017, End date: Aug 14, 2019,

The developing neocortex consists of two major neuronal subtypes–pyramidal neurons and interneurons. These two subtypes come together in the cortical plate, forming cortical circuits that can integrate and respond to external and internal stimuli. Despite recent advancement in the research on cortical networks of the developing brain, the mechanism involved in cortical circuit assembly remains rel ...
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 1

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10/66 ten years on – monitoring and improving health expectancy by targeting frailty among older people in middle income countries (LIFE2YEARS1066)

Start date: Aug 1, 2014, End date: Jul 31, 2019,

... on health. Inequalities in HE (disability-free and dependence-free life expectancies) will be evaluated within and between countries. Multistate analyses will assess their determinants, unpacking influences of socioeconomic position, chronic disease and underlying frailty on incidence of disability and care-dependence, recovery and mortality, thus identifying priorities for prevention and interve ...
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 1

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Valuing Innovation Options and Policy Flexibility Under Uncertainty (INNOVATIONOPTIONS)

Start date: Aug 1, 2016, End date: Jul 31, 2019,

This proposal consists of a two-year outgoing phase (1.5 years at MIT and 6-month secondment at LUISS U. in Italy) and one-year re-integration phase at King’s College London. Following advanced innovation training, it aims to develop new ideas and frameworks based on real options theory to appraise innovation options and policy flexibility. Besides training/development and dissemination, the propo ...
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 1

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Aggression in Children: Unraveling gene-environment interplay to inform Treatment and InterventiON strateg (ACTION)

Start date: Jun 1, 2014, End date: May 31, 2019,

Aggression inflicts a huge personal, psychological and financial burden on affected individuals, their relatives, and society at large. Despite large scientific, preventive, and treatment investments, no decrease in aggressive behavior is seen. This calls for a shift to new approaches. By capitalising on comprehensive longitudinal cohorts, recent advances in genetic, biological, epidemiological, a ...
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 12

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Lifecourse biological pathways underlying social differences in healthy ageing (LIFEPATH)

Start date: May 1, 2015, End date: Apr 30, 2019,

"The dramatic differentials in healthy ageing, quality of life and life expectancy between individuals of different socioeconomic groups, is a major societal challenge facing Europe. The overarching aim of the LIFEPATH project is to understand the determinants of diverging ageing pathways among individuals belonging to different socio-economic groups. This will be achieved via an original study de ...
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 18

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Pooling Activities, Resources and Tools for Heritage E-research Networking, Optimization and Synergies (PARTHENOS)

Start date: May 1, 2015, End date: Apr 30, 2019,

...tions to the same problems.PARTHENOS will address and provide common solutions to the definition and implementation of joint policies and solutions for the humanities and linguistic data lifecycle, taking into account the specific needs of the sector that require dedicated design, including provisions for cross-discipline data use and re-use, the implementation of common AAA (authentication, autho ...
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 19

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Tracing the global fertility chain- A new political economy of outsourced reproduction (globalfertilitychain)

Start date: May 1, 2017, End date: Apr 30, 2019,

...ed the reproductive bio-economy, organised around the “flow” of reproductive substances and organs, such as egg cells, embryos and wombs, women are increasingly commercialising their bodies by working as oocyte vendors, surrogate mothers or tissue providers. There is fundamental disagreement among scholars and policy makers on how the reproductive bio-economy should be organised. Market critics pr ...
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 1

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European Holocaust Research Infrastructure (EHRI)

Start date: May 1, 2015, End date: Apr 30, 2019,

The European Holocaust Research Infrastructure (EHRI) project seeks to transform archival research on the Holocaust. The vision of EHRI is to integrate the data, services and expertise of existing Holocaust infrastructures on an unprecedented scale. It will allow researchers from across the globe transnational and virtual access to the integrated infrastructure, and provide them with innovative di ...
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Ego-media: The impact of new media on forms and practices of self-presentation (EGO-MEDIA)

Start date: May 1, 2014, End date: Apr 30, 2019,

...ubjectivity, individuality, self-intelligibility, agency, creativity, privacy, and sociability. Based in the interdisciplinary Centre for Life-Writing Research in the School of Arts and Humanities at King’s College London, it will combine a humanistic, life-writing theory approach with an interdisciplinary methodology, in collaboration with researchers from Sociolinguistics, Culture Media and Crea ...
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MIDDLE EAST AND NORTH AFRICA REGIONAL ARCHITECTURE: MAPPING GEOPOLITICAL SHIFTS, REGIONAL ORDER AND DOMESTIC TRANSFORMATIONS (MENARA)

Start date: Apr 1, 2016, End date: Mar 31, 2019,

The ‘Middle East and North Africa Regional Architecture: mapping geopolitical shifts, regional order and domestic transformations’ -the MENARA Project- will study the geopolitical order in the making in the South and East Mediterranean Countries and the Middle East amid all deep-reaching social and political changes unfolding since 2010. The project aims at describing the main features of the regi ...
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 14

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Multidisciplinary Approaches to Translational Research In Conduct Syndromes (MATRICS)

Start date: Mar 1, 2014, End date: Feb 28, 2019,

...ity coupled to the differential impairment of three basic neural functions: 1) regulation of control mechanisms of aggression, 2) emotional value rating of others, and 3) empathy and moral decision making. MATRICS will employ the same psychological tasks assessing 1), 2) and 3) in animal aggression models and human CD samples concurrent with the assessment of neural, neurochemical, (epi)-genetic a ...
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