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One of the key issues in biology is determining the mechanisms underlying the response of organisms to changes in their environment. It is known that ability of cells to sustain and recover after stress conditions depends on a well-developed and complex network of protein chaperones and co-chaperones. This proposal addresses fundamental questions in a recently discovered subgroup of molecular chap ...
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 FINISHED 
A major goal of Systems Biology is to understand the design principles underlying Biological Networks. Of particular interest are the computational roles of network motifs - circuits that appear in the network multiple times, significantly more than randomly expected. But why would such circuits evolve over and over again in the network?While extensively studied in transcriptional networks, the e ...
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