Archive of European Projects

23 European Projects Found

Searched on 125080 European Projects

 ONGOING 
Molecular in vitro diagnostics and biomedical research have allowed great progress in personalised medicine but further progress is limited by insufficient guidelines for pre-analytical workflow steps (sample collection, preservation, storage, transport, processing etc.) as well as by insufficient quality assurance of diagnostic practice. This allows using compromised patients’ samples with post c ...
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 21

 ONGOING 
Instruct-Ultra aims to advance the scope and efficiency of implementation of Instruct and consolidate the foundations for long-term sustainability. This will be achieved through specific objectives: expand Instruct membership to new Member States and increase global links; engage new user communities; improve efficiencies in service delivery; improve data capture and management; adjust the scale a ...
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 19

 ONGOING 
Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials.iNEXT (infrastructure for NMR, EM and X-rays for Translational rese ...
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 23

 ONGOING 
Ageing is the major risk factor for idiopathic PARKINSON'S DISEASE (PD), the first motor neurodegenerative disorder (in EU 1% in 65+; about 4% in 80+). The most recent conceptualizations of ageing and PD indicate that they share basic mechanisms, e.g. accumulation of senescent cells and propagation phenomena such as inflammaging mirrored in PD by neuro-inflammaging in brain that foster a prion-lik ...
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 10

 ONGOING 
The social and economic challenges of ageing populations and chronic disease can only be met by translation of biomedical discoveries to new, innovative and cost effective treatments. The ESFRI Biological and Medical Research Infrastructures (BMS RI) underpin every step in this process; effectively joining scientific capabilities and shared services will transform the understanding of biological m ...
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 39

 FINISHED 

World-wide E-infrastructure for structural biology (West-Life)

Start date: 01 Nov 2015, End date: 31 Oct 2018,

The focus of structural biology is shifting from single macromolecules produced by simpler prokaryotic organisms, to the macromolecular machinery of higher organisms, including systems of central relevance for human health. Structural biologists are expert in one or more techniques. They now often need to use complementary techniques in which they are less expert. Instruct supports them in using m ...
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 10

 FINISHED 
In the coming decade a significant number of the 500.000.000 European (EU/EEA) citizens will have their genome determined routinely. This will be complemented with much cheaper (currently ~20 Euro per measurement) acquisition of the metabolome of biofluids (e.g. urine, saliva, blood plasma) which will link the genotype with metabolome data that captures the highly dynamic phenome and exposome of p ...
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 17

 FINISHED 
The INDIGO-DataCloud project (INDIGO for short) aims at developing a data/computing platform targeted at scientific communities, deployable on multiple hardware, and provisioned over hybrid (private or public) e-infrastructures. This platform will be built by leading European developers, resource providers, e-infrastructures and scientific communities in order to ensure its successful exploitation ...
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 27

 FINISHED 
Over the last decade, the European Grid Infrastructure (EGI) has built a distributed computing and data infrastructure to support over 21,000 researchers from many disciplines with unprecedented data analysis capabilities. EGI builds on the European and national investments and relies on the expertise of EGI.eu - a not-for-profit foundation that provides coordination to the EGI Community, includin ...
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 43

 FINISHED 
A network combining 9 academic research groups and 4 collaborating industrial companies is proposed to train the next generation of PhD students and post-doctoral researchers, in developing and applying novel experimental and theoretical methods in the NMR spectroscopy of systems containing paramagnetic metals. The assembled team, with researchers distributed throughout the EU, will investigate a ...
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 12

 FINISHED 
The ESFRI infrastructures in Biological and BioMedical Sciences face substantial challenges in accessing and sharing data and resources. The BioMedBridges consortium brings together the six established ESFRI infrastructures with common goals to define, implement and deliver data interoperability across the biological and biomedical domains.The first objective is to ensure that interoperable stand ...
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 26

 FINISHED 
Metabolomics is an important phenotyping technique for molecular biology and medicine. It assesses the molecular state of an organism or collections of organisms through the comprehensive quantitative and qualitative analysis of all small molecules in cells, tissues, and body fluids. Metabolic processes are at the core of physiology. Consequently, metabolomics is ideally suited as a medical tool t ...
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 16

 FINISHED 
Recent evidence shows that a large share of proteins gain functional advantages by remaining natively unstructured, either completely or partially, thus challenging well-established concepts in structural biology. In order to characterize the highly dynamical nature of such “intrinsically disordered proteins”, and follow their (possible) reorganization by interacting with partners, new integrated ...
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 10

 FINISHED 

NMR for Structural Biology (Bio-NMR)

Start date: 01 Sep 2010, End date: 31 Aug 2014,

In the past two decades spectacular insight into basic principles of life has been obtained from paradigmatic high-resolution structural investigations providing a rational basis for biological experiments. NMR is an indispensable enabling technology for determining such structures and their interactions in solution, the immobilized state and living cells. The power of NMR to link structural, dyna ...
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 20

 FINISHED 
"According to 2007 Eurostat statistics, there is a robust need to better understanding the nutritional existing barriers to healthy nutrition of 79 million EU-27 citizens at-risk-of-poverty. These European subclusters and ethnic populations have in common low purchasing power, limited education and the highest risk of diet-related diseases due to sub-optimal nutrition. CHANCE project will i) defin ...
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 19

 FINISHED 

Word Wide NMR (WW-NMR)

Start date: 01 May 2010, End date: 30 Apr 2014,

and institutions specialised in all aspects of NMR spectroscopy in Europe with newly developed laboratories in five other countries. It builds on EU-funded infrastructures and will enable the creation of strategic and sustainable links with nine Partners from countries outside Europe. In return Third Country Partners will gain access to highly sophisticated NMR equipment. NMR spectroscopy is a bro ...
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 7

 FINISHED 

A worldwide e-Infrastructure for NMR and structural biology (WeNMR)

Start date: 01 Nov 2010, End date: 31 Oct 2013,

Structural biology and life sciences in general, and NMR in particular, have always been associated with advanced computing. The current challenges in the post-genomic era, with their focus on biomolecular interactions, call for virtual research platforms that provide the worldwide research community with both user-friendly tools, platforms for data analysis and exchange, and an underlying e-infra ...
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 9

 FINISHED 
"In vitro diagnostics have allowed a great deal of progress in medicine but are limited by two factors: (a) the lack of guidelines in collection, handling, stabilisation and storage of biosamples which limits the reproducibility of subsequent diagnoses, and (b) its scale is restrained to the cellular level. To address this first point, this IP, SPIDIA, built of clinicians, academics, tool and assa ...
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 17

 FINISHED 
"Nuclear magnetic resonance (NMR) spectroscopy is a key technology for research in the modern Life Sciences, with an increasing impact on human health. This technology is unique in new areas of molecular systems biology providing detailed insight into protein-protein and protein-ligand interactions. NMR Research Infrastructures (RIs) are of primary importance here; they offer the resources necessa ...
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 21

 FINISHED 

IT Future of Medicine (ITFoM)

Start date: 01 May 2011, End date: 30 Apr 2012,

Data-rich, individualised medicine poses unprecedented challenges for IT, in hardware, storage and communication. We propose a data-driven, individualised medicine of the future, based on molecular/physiological/anatomical data from individual patients. We shall make general models of human pathways, tissues, diseases and ultimately of the human as a whole. Individualised versions of the models, ...
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 25

 FINISHED 
"EPISODE’s goal is to maximize the regional benefits of Structural Biology Research Infrastructures in NMR and associated technologies for the economic development of the pharma/biotech industries in Tuscany, Berlin-Brandenburg and beyond. As traditional Structural Biology research moves towards new horizons, a major goal has become a systemic view of Life, implying a change of focus from single ...
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 12

 FINISHED 

HGF/SF and MET in metastasis (SFMET)

Start date: 01 Apr 2008, End date: 30 Sep 2011,

"The growth and motility factor HGF/SF and its receptor MET define a paracrine signalling system which controls the migration of several cell lineages in embryogenesis and tissue repair. In a large number of human tumours, cancer cells hijack HGF/SF and MET signalling in order to invade adjacent tissue and initiate metastasis. The evidence for this is strong, broad and consistent and highlights ...
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 4

 FINISHED 

Integrated Structural Biology Infrastructure (INSTRUCT)

Start date: 01 Apr 2008, End date: 31 Mar 2011,

Structural biology in the next two decades aims to integrate structural knowledge at different resolution levels into specific cellular contexts, with a temporal component, to underpin biomedical sciences. This challenge requires the seamless integration of techniques providing information in different resolution ranges. INSTRUCT will link the information obtained by the major structural biology ...
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 15