THREE DIMENSIONAL TISSUE CULTURING IN THE LOCAL GRADIENT MAGNETIC FIELD

Created on 07 Apr 2016
National Science Center "Kharkov Institute of Physics and Technology" user picture

National Science Center "Kharkov Institute of Physics and Technology"

Research Institute

Creator



Looking for Partnership

Looking for Lead Partner


Download File

The idea is aimed to apply a method for creating gradient magnetic fields in biotechnology to control the three-dimensional tissue culturing and to develop methods for creating of local magnetic fields and its effect on tissue culturing process.

Our team has developed the elastic resin-bonded magnets with a specific geometry of magnetic field distribution. This allows meeting several requirements to the external magnetic field: specific geometry and uniform distribution of magnetic field at the required distance.

Also we have applied the elastic magnets for development of a new approach to the creation of conditions for growing cells in a 3D space. This involves application of small gradient magnetic fields, due to which energetic 3D space for growing cells is created. Such technology can be applied in the field of tissue engineering for creation of biological implants as an alternative to existing methods using biopolymer matrices or magnetic nanoparticles which are injected into the cell culture for directional cell growth.

Preliminary analysis of the influence of the proposed conditions on the growth of epitelium-like cell cultures of pig embryo kidney have shown positive results for creation of cells in a 3D space as well as improved adhesion and proliferation of cell cultures. From our point of view, small magnetic gradient fields directed in a 3D space in a certain way can be used for creation of a new method in the field of tissue engineering and regenerative medicine. It should be noted that application of the proposed resin-bonded magnets is not limited to culturing the cells under conditions of magnetic field gradient in vitro. These magnets can also be used for regeneration of burned tissues.

We are looking for cooperation with the specialists in the field of biotechnologies. This cooperation allows development of the method using small gradient magnetic fields, due to which energetic 3D space for growing biological tissues in vitro having the properties characteristic for body tissues can be created.

 

 


 Biotechnology
 Innovation & Research
 Nanotechnology and Nanosciences
 Industrial Engineering

Recommended Calls for This Idea
If you know a call that can work with this idea

recommend a call  

Looking for Similar Ideas?
Here are suggestions of similar ideas

A 1,000 healthy donors cohort to define Immune Response variability

Created on 23 May 2017
...
 Biotechnology
 
 Innovation & Research
 
...

The Milieu Intérieur project, "Genetic & Environmental Determinants Of Immune Phenotype variance: Establishing A Path Towards Personalized Medicine", is an ambitious population-based study coordinated by the Institut Past ...

Interested in a Partnership (Bar-Ilan University)

Created on 28 Mar 2017
...
 Biotechnology
 
 Innovation & Research
 
 Nanotechnology and Nanosciences
 
...

Nano biotechnology projects in fields of drug delivery systems (DNA/RNA technologies, etc..), mechanically hard inorganic composite nanomaterials and antibacterial nanoparticles/MRI-enablig strong innovative composite particles

Interested in a Partnership (ProxAgen Ltd.)

Created on 28 Mar 2017
...
 Biotechnology
 
 Innovation & Research
 
...

We are looking for pivotal partnership in diagnostic test development, set-up and validation