Taste perception, oxidative damage and colon microenvironment in colorectal carcinogenesis: impacts on the disease risk, prognosis and prevention.

Created on 08 Apr 2016
Nutrition and Diagnostics Conference user picture

Nutrition and Diagnostics Conference

Research Institute

Creator



Looking for Partnership

Looking for Lead Partner


Colorectal cancer (CRC) develops as a consequence of inherited multiple low-risk variants in concurrence of environmental factors. Nutrition and intestinal microbiota exert an effect on DNA damage accumulation and its repair (maintaining universal genomic stability and preserves cellular functions), intestinal metabolism, immunological activity and substantially affect the efficacy of chemotherapy. Integrated studies should unveil in humans the role of A) Taste perception, intestinal microbiota, DNA damage and repair in CRC risk (CRC patients vs. control individuals); B) Intestinal microbiota, DNA damage and repair as prognostic markers of CRC progression, treatment efficacy and survival. Monitoring of taste perception and intestinal microenvironment with simultaneous determinations of DNA damage response and repair in cancer patients represent substantial novel contribution. Our project further aims to integrate above parameters into the prognostic and therapeutical considerations, which ultimately result in individually tailored therapy and improved quality of the life.


 Health Care
 Nutrition
 Research

Recommended Calls for This Idea
If you know a call that can work with this idea

recommend a call  

Looking for Similar Ideas?
Here are suggestions of similar ideas

Consortium building for IMI call-Topic 6

Created on 07 Sep 2017
...
 Health Care
 
...

Nanovex Biotechnologies is a Spanish SME that offers services in the nanobiotechnological field and it deals with the production of drug delivery systems for cancer therapy and brain delivery, metallic and polymer nanoparticles imaging b ...

FUNCTIONAL UNITS

Created on 01 Sep 2017
...
 Health Care
 
...

Apart from the units mentioned above, our Centre involves other ones. For instance: 1. Genomics Unit. It carries out different lines of research such as genomics and transcriptomics of olive tree, development and youth period of olive tr ...

searching partners from TUNISIA

Created on 04 Aug 2017
...
 Health Care
 
...

Federsanità-ANCI from Italy is an institutional Federation that associates Public Local Health Units, Public Hospital Trustees and Italian Municipalities. Federsanità-ANCI is drafting a project to be submitted under the nex ...