PSD-95 inhibition in neurogenerative disorders

Created on 14 Jul 2017

Avilex Pharma

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Avilex Pharma has developed an exceptionally high-affinity inhibitor of the intracellular scaffolding protein, postsynaptic density protein 95 (PSD-95), which bridges the NMDA glutamate receptor and neuronal nitric oxide synthase (nNOS). Avilex Pharma is pursuing this peptide-based compound as a potential drug candidate for the treatment of ischaemic stroke and seeks partners to evaluate these in in vitro and in vivo models of stroke and other related neurodegenerative conditions.


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