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Targeting LRP5 to Increase Bone Formation in Osteoporosis (TALOS)

Start date: May 1, 2008, End date: Apr 30, 2011,

"The balance between bone resorption and bone formation determines the mass and structural integrity of the skeleton and is disturbed in osteoporosis. In contrast to the molecular mechanisms regulating bone resorption, knowledge of the mechanisms regulating bone formation is limited. A recent breakthrough has been the identification of a link between bone mass in humans with rare bone disorders an ...
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