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The use of Methylated DNA Immunoprecipitation MeDIP in cancer for better clinical management (CANCERDIP)
Start date: Jan 1, 2008, End date: Jun 30, 2011,
"Aberrant DNA methylation is the most common molecular lesion of the cancer cell. Neither gene mutation nor cytogenetic abnormalities are as common in human tumours as DNA methylation alterations. The stability of our genome and correct gene expression is maintained to a great extent thanks to a perfectly preestablished pattern of DNA methylation and histone modifications. In cancer this idealisti ...
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