5 European Projects Found
Searched on 125080 European Projects
FINISHED
Chromatin Dynamics in Development and Disease (Chromatin3D)
Start date: Jan 1, 2015, End date: Dec 31, 2018,
The cell nucleus is organized and compartmentalized into a highly ordered structure that contains DNA, RNA, chromosomal and histone proteins which make up a structure called chromatin. The dynamics associated with these various components are responsible for regulating physiological processes and the overall stability of the genome. The destabilization of such regulatory mechanisms that act on the ...
Read Project
12
Partners Participants
FINISHED
Control of metabolic and inflammatory pathways by nuclear receptors (NR-NET)
Start date: Sep 1, 2013, End date: Aug 31, 2017,
NR-NET is a multidisciplinary consortium, whose activities are directed towards the understanding of the role of Nuclear Receptors (NRs) and coregulators in metaflammatory disease. Metaflammation - metabolic disorders linked to chronic inflammation – is an emerging concept explaining the pathogenesis of a wide-spectrum of diseases. Since several nuclear receptors can directly sense metabolic alter ...
Read Project
11
Partners Participants
FINISHED
Transposon-based, targeted ex vivo gene therapy to treat age-related macular degeneration (AMD) (TARGETAMD)
Start date: Nov 1, 2012, End date: Oct 31, 2016,
Age-related Macular Degeneration (AMD), a neurodegenerative disease of the retina, is a major cause of blindness in elderly people. Due to the aging population, AMD has been referred to as a “time bomb” in society. In the exudative form of AMD, high levels of vascular endothelial cell growth factor (VEGF) and low levels of pigment-epithelial derived factor (PEDF), an inhibitor of vascularization a ...
Read Project
16
Partners Participants
FINISHED
Transglutaminase in disease: a novel therapeutic target? (TRANSPATH)
Start date: Nov 1, 2011, End date: Oct 31, 2015,
"TRANSPATH is a multisectorial Network designed to facilitate the exchange of knowledge and technology between 7 leading European research teams and 3 SME partners and 2 associate SME Partners involved in basic and applied research into transglutaminase (TG) related human diseases. Its ambitions are to accelerate the development of new strategies for the treatment and diagnosis of human diseases ...
Read Project
12
Partners Participants
FINISHED
The Commercialisation of Transglutaminase (TRANSCOM)
Start date: Jul 1, 2010, End date: Jun 30, 2014,
The TRANSCOM project is designed to facilitate the exchange of knowledge and technology between 3 leading European research teams and 4 SMEs each with an interest in the protein crosslinking enzymes Transglutaminases. Transglutaminases are a widely distributed group of enzymes that catalyse the post-translational modification of proteins by the formation of isopeptide bonds or by deamidation of pr ...
Read Project
