5 European Projects Found
Searched on 125080 European Projects
FINISHED
The Human Brain Project (HBP)
Start date: Oct 1, 2013, End date: Sep 30, 2016,
Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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116
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Genetic and Epigenetic Networks in Cognitive Dysfunction (GENCODYS)
Start date: May 1, 2010, End date: Apr 30, 2015,
Mutations in about 400 different genes have been associated with Cognitive Disorders (CD), such as mental retardation, autism, neurodegenerative disorders, and psychiatric disorders. Whereas CD impose a major medical and socio-economical problem, there are no systematic studies that aim to provide insight into common mechanisms in CD. We propose a systems biology approach to gain insight into comm ...
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15
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Synaptic Systems: dissecting brain function in health and disease (SYNSYS)
Start date: Jul 1, 2010, End date: Dec 31, 2014,
Major disorders of the Central Nervous System (CNS) affect one in three people in the developed world, often seriously disable the affected individual, and together account for the single largest burden on the healthcare systems of the EU. Most of these disorders act at the neuronal synapse, a cellular organelle comprising in the order of 2000 proteins. Pleiotropy, cross-talk between proteins and ...
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19
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European Consortium on Synaptic Protein Networks in Neurological and Psychiatric Diseases (EUROSPIN)
Start date: Jan 1, 2010, End date: Jun 30, 2014,
"Signalling at nerve cell synapses - a key determinant of all aspects of brain function - depends on the function of hundreds of synaptic proteins and their interactions. Numerous recent studies showed that a wide range of neurological and psychiatric diseases are 'synaptopathies' whose onset and progression are due to mutations of synaptic proteins and subsequent synaptic dysfunctions. EUROSPIN w ...
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19
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The PharMEA Platform: Multi-Electrode Array technology based platform for industrial pharmacology and toxicology drug screening (PharMEA)
Start date: Sep 1, 2009, End date: Nov 30, 2011,
The project PharMEA is based on the technology platform of multi-electrode arrays, which have been widely used for electrophysiological experiments on neuronal and cardiac tissues. Some of the key advantages of MEA technology include ease of use, non-invasive measurements and simultaneous multi-site recording & stimulation capability. Despite these key advantages, MEA technology utilization has re ...
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