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The goal of NeuroSign is to create a national Centre of Excellence for the study of Neurosignalling during nervous system function and dysfunction, through capacity development of the neuroscience potential of the Hellenic Pasteur Institute. Our group integrates the activities of 18 researchers in topical issues ranging from the study of neuromuscular and neuroimmune interactions to neurodevelopme ...

Cys-loop receptors (CLRs) form a superfamily of structurally related neurotransmitter-gated ion channels, comprising nicotinic acetylcholine, glycine, GABA-A/C and serotonin (5HT3) receptors, crucial to function of the peripheral and central nervous system. CLRs cover a wide spectrum of functions, ranging from muscle contraction to cognitive functions. CLR (mal)function is linked to various disord ...