Search for European Projects

2 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Clinical Development of Nitisinone for Alkaptonuria (DEVELOPAKURE)

Start date: Nov 1, 2012, End date: Apr 30, 2018,

DevelopAKUre is a proposal to fund the clinical development of an orphan designated drug, nitisinone, for the treatment of a rare Mendelian disease, Alkaptonuria (AKU). AKU is a genetic deficiency of homogentisic acid dioxygenase, causing high levels of homogentisic acid (HGA). Oxidation of HGA to pigment polymer, termed ochronosis, alters connective tissues. This leads to multisystemic damage dom ...
Read Project

 14

 FINISHED 

Orphan Drug for Acanthamoeba Keratitis (ODAK)

Start date: Dec 1, 2012, End date: Nov 30, 2017,

This project will undertake preclinical and clinical research of the Orphan Drug Polihexanide (PHMB). The main objective is to provide a safe and effective drug for the treatment of the rare ocular disease Acanthamoeba keratitis (AK) tested according to international regulatory standards. This debilitating infectious disease is caused by a free living protozoan which, in the absence of treatment ...
Read Project

 6