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Structure-function analysis of mRNA metabolism by Ccr4-Not (POL2-CCR)

Start date: Sep 1, 2014, End date: Aug 31, 2016,

"Eukaryotic gene expression is tightly regulated at all stages of the mRNA life cycle, from mRNA synthesis in the nucleus to mRNA degradation in the cytoplasm. Defects in gene regulation cause serious defects in cells, and severe pathologies in humans, such as cancer, diabetes, and cardiovascular disease. The host lab recently made the seminal discovery that mRNA synthesis and degradation are coup ...
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