2 European Projects Found
Searched on 125080 European Projects
FINISHED
New Models for Preclinical Evaluation of Drug Efficacy in Common Solid Tumours (PREDECT)
Start date: Feb 1, 2011, End date: Apr 30, 2016,
Traditional preclinical discovery methods, particularly for target validation, poorly predict drug efficacy, causing a high attrition rate in costly late-stage clinical trials. The PREDECT consortium will focus on complex but transferable, next generation in vitro and in vivo models for breast, prostate and lung cancers. Models will be investigated for their improved potential to validate novel th ...
Read Project
23
Partners Participants
FINISHED
"Generation and Evaluation of ""Next-generation"" Antibody-Toxin-Conjugates for Cancer Therapy" (MABTOX)
Start date: Oct 1, 2013, End date: Dec 31, 2015,
Therapeutic antibodies have transformed cancer therapy during the last decade, due to their high selectivity of targeting cancer cells in comparison to standard small molecule chemotherapy. Most recently, the coupling of cellular toxins to therapeutic antibodies has demonstrated an even greater efficacy in the therapy of cancer and the first, highly potent antibody drug conjugate (ADC), Adcetris®, ...
Read Project
