Search for European Projects

3 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Molecular basis of the outer membrane permeability (TRANSLOCATION)

Start date: Jan 1, 2013, End date: Dec 31, 2017,

Overcoming the barriers that the cell envelope and efflux pumps provide to Gram-negative bacteria is a major bottleneck in the discovery and development of new antibiotics. To respond to this Call we are extending our current network on antibiotic translocation and propose an ambitious project ranging from identification of novel resistance mechanisms in clinical bacterial isolates to crystallizat ...
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 FINISHED 

MOLECULAR BASIS OF ANTIBIOTIC TRANSLOCATION (Translocation)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

Multidrug resistant bacteria are now ubiquitous in both hospitals and the larger community. Drug-resistant pathogens are becoming increasingly pervasive, for example, the resurrection of tuberculosis provides one ominous example highlighting the risk associated with evolved drug resistance. Moreover, many pharmaceutical companies abandoned this field and no truly novel active antibacterial compoun ...
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 11

 FINISHED 

Development of a new method for brief compound exposures to ion channels proteins using an automated patch clamp platform (NanionLigand)

Start date: Jun 15, 2009, End date: Jun 14, 2012,

The gold standard for obtaining data on ion channel function is the patch clamp method. The patch clamp technique is very labor intensive and has ultra low data throughput which has been highly motivating for the development of automated patch clamp systems.Nanion has developed a technology for performing automated patch clamp recordings on planar glass substrates, with comparable recording qualit ...
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 1