5 European Projects Found
Searched on 125080 European Projects
FINISHED
Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI)
Start date: Oct 1, 2013, End date: Mar 31, 2020,
Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 p ...
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44
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FINISHED
Autologous Stem Cell Seeded Tissue Engineered Trachea (TETRA)
Start date: Jan 1, 2016, End date: Dec 31, 2019,
CLINICAL PROBLEM AND UNMET NEEDThere are 11,827 patients with severe structural airway disease in Europe. Even with the current standard of care, when hospitalised this group of patients has a 22% risk of dying. Patients are currently subjected to repeated surgical interventions (stent insertion) which have a high failure rate. Other therapeutic strategies under development include synthetic trac ...
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14
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Novel Stromal Cell Therapy for Diabetic Kidney Disease (NEPHSTROM)
Start date: May 1, 2015, End date: Apr 30, 2019,
Type 2 diabetes will affect >500 million adults by 2040 and its secondary complications will generate enormous socioeconomic costs - in particular, diabetic kidney disease (DKD), which is already the most common cause of chronic kidney disease. DKD is associated with greatly increased mortality and frequently progresses to end stage renal failure. Pharmacotherapy, dialysis and transplantation repr ...
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12
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MEsenchymal stem cells to Reduce Liver INflammation (MERLIN)
Start date: Feb 1, 2014, End date: Jan 31, 2018,
"Prevalence of liver disease is c6% (29 million people) in the EU with mortality rates from chronic liver diseases estimated at 14.3 per 100.000 in the EU-25 in 2004. Most liver diseases have a significant inflammatory component that underpins liver damage and fibrogenesis, yet current therapies have limited effectiveness. Safe novel anti-inflammatory therapies would satisfy a large unmet need for ...
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9
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A Europe-wide Strategy to enhance Transplantation of highly sensitized patients on basis of Acceptable HLA Mismatches (EUROSTAM)
Start date: Dec 1, 2012, End date: Nov 30, 2015,
The presence of donor specific HLA antibodies is a contra-indication for renal transplantation. Highly sensitized patients accumulate and often die on the transplant waiting lists as it is almost impossible to find donors towards which they don’t have antibodies. The acceptable mismatch program of Eurotransplant has shown to be an effective tool to enhance successful transplantation of highly sens ...
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