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Signalling network regulating tooth development (Tooth)

Start date: Apr 1, 2008, End date: Mar 31, 2011,

In teeth sequential and reciprocal interactions between epithelium and ectomesenchyme play a pivotal role in their development. A progress has been made in identifying various key transcription factors and signalling molecules participating in epithelial–mesenchymal signalling, involving different pleiotropic morphogens, such as bone morphogenetic proteins, fibroblast growth factors, hedgehog and ...
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