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TOPIC: Targeting Cytotoxic Protein Oligomers (TOPIC)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

"Parkinson's disease and Huntington's disease are highly debilitating diseases for which no disease modifying treatment is available. This EID proposal, called TOPIC (Targeting Cytotoxic Protein Oligomers), will train 2 ESRs to target the oligomeric protein aggregate which accumulates in these diseases. These oligomers occur under conditions which eventually lead to the accumulation of fibrillar a ...
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