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Memory loss in Alzheimer disease: underlying mechanisms and therapeutic targets (MEMOSAD)
Start date: Jan 1, 2008, End date: Jun 30, 2011,
...ced synaptotoxicity and at developing disease-modifying therapeutics for the prevention of memory loss in Alzheimer disease (AD). Insoluble aggregates of the two proteins provide the pathological hallmarks of this incurable brain disorder. Early stage AD is characterized by a remarkably pure impairment of declarative memory and several lines of evidence suggest that this memory impairment is indep ...
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