3 European Projects Found
Searched on 125080 European Projects
FINISHED
Identification and functional characterization of genetic cancer risk variants (CancerGene)
Start date: Mar 1, 2008, End date: Feb 29, 2012,
This Industry-Academia Partnership and Pathways (IAPP) joins three groups which have hitherto focused on different aspects of cancer genetics. deCODE genetics (deCODE) has recently identified several genetic risk variants that are associated with increased risk of cancer, including two distinct genetic prostate cancer risk variants on chromosome 8q24. The University of Torino (UNITO) group has id ...
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3
Partners Participants
FINISHED
Understanding and fighting metastasis by modulating the tumour microenvironment through interference with the protease network (MICROENVIMET)
Start date: Mar 1, 2008, End date: Feb 29, 2012,
"The MICROENVIMET project proposes innovative approaches for building a comprehensive understanding of the interplay between cancer cells and their microenvironment both at primary and secondary sites. The objectives are to identify molecular pathways involved in the regulation of metastatic dissemination to lung, liver, lymph node and bone. To achieve these objectives, the original experimental a ...
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9
Partners Participants
FINISHED
HGF/SF and MET in metastasis (SFMET)
Start date: Apr 1, 2008, End date: Sep 30, 2011,
"The growth and motility factor HGF/SF and its receptor MET define a paracrine signalling system which controls the migration of several cell lineages in embryogenesis and tissue repair. In a large number of human tumours, cancer cells hijack HGF/SF and MET signalling in order to invade adjacent tissue and initiate metastasis. The evidence for this is strong, broad and consistent and highlights ...
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