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HGF/SF and MET in metastasis (SFMET)

Start date: Apr 1, 2008, End date: Sep 30, 2011,

"The growth and motility factor HGF/SF and its receptor MET define a paracrine signalling system which controls the migration of several cell lineages in embryogenesis and tissue repair. In a large number of human tumours, cancer cells hijack HGF/SF and MET signalling in order to invade adjacent tissue and initiate metastasis. The evidence for this is strong, broad and consistent and highlights ...
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