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Over 40 European Projects Found

Searched on 125080 European Projects

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"This path-breaking interdisciplinary project critically analyses the impact of the increased prominence of the individual in the theory and practice of armed conflict. The ‘individualisation of war’, while based on powerful normative and technological developments, places enormous strain on the actors most actively engaged in contexts of conflict: the governments and armed forces of states, inter ...
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"In the last 10 years, power electronics has moved significantly towards the electric grid, making it more flexible and decentralized. Still important challenges remain. One of the most thrilling is re-inventing the distribution transformer after more than 125 years since its first use in the electrification of a city. In fact, actual distribution transformers can no longer fulfill the requirement ...
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Lipids play crucial roles in metabolism, immunity and cancer. In addition to their function as inflammatory mediators, lipids serve as antigens presented by CD1d and activate a subset of T cells called natural killer T (NKT) cells. While NKT cells are critical for human immunity, their uncontrolled activation contributes to inflammatory bowel disease (IBD), a group of diseases characterized by chr ...
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VOX-Pol is a 60-month, €5+ million project that integrates the world’s leading researchers and research groups in Violent Online Political Extremism (VOPE), to include those researching the intersection of terrorism and the Internet (incl. violent jihadists, violent separatists, etc.), the online activities of the extreme Right, the potential for violent online radicalisation, etc., in order to:1. ...
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Imparting chirality to non-chiral metal surfaces by adsorption of chiral modifiers is a highly promising route to create effective heterogeneously catalyzed processes for production of enantiopure pharmaceuticals. A molecular-level understanding of enantioselective processes on chiral surfaces is an importance prerequisite for the rational design of new enantiospecific catalysts. With the research ...
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Adhesion is a key event for eukaryotic cells to establish contact with the extracellular matrix and other cells. It allows cells to quickly adapt to mechanical changes in their environment by either adhesion reinforcement or release. Understanding and mimicking the interplay between adhesion reinforcement and release could result in novel cell-inspired adaptive materials. In order to ultimately be ...
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Smart surfaces with switchable properties hold great promise for future integrated sensors. Azobenzene molecules have been demonstrated to switch reversibly between the trans and cis isomer with picosecond time constants, when triggered with an external light source. Due to the different molecular geometries and electronic properties of the isomers, these may be used as molecular switches for real ...
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Tropical forests in the changing earth system (T-FORCES)

Start date: Jul 1, 2012, End date: Jun 30, 2018,

The ambition of this proposal is to determine, from the ground up, the changing role of tropical forests in the global carbon cycle. The scientific objectives are: (1) Determine the trajectory of change in remaining tropical forests, (2) Unravel the drivers of change, (3) Gauge the sensitivity of forests to the climate change threat, and (4) Scale the findings to the present and future earth syste ...
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The Underbelly of the Indian Boom: Adivasis and Dalits (UNDERINDIA)

Start date: Jul 1, 2013, End date: Jun 30, 2018,

In recent decades India has experienced exceptionally high economic growth rates, becoming one of the world’s fastest growing major economies. Yet, the redistribution of the fruits of economic growth – the trickle down effects of growth – have been negligible for vast swathes of India’s population, most of who live in the countryside. The demographics of the poor are starkly socially marked. Econo ...
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Lateral gene transfer (LGT) is the process by which prokaryotes acquire DNA across wide taxonomic boundaries and incorporate it into their genome. Accumulating evidence shows that LGT plays a major role in prokaryote evolution. The biological and evolutionary significance of lateral gene transfer has broad implications for our understanding of microbial biology, not only in terms of evolution, but ...
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The research proposed here will use a novel and fully-integrated data-modelling approach to provide a step-change in our understanding of the nature and drivers of climate variability and change on the societally-relevant timescales of decades to centuries. Identifying the causes of observed changes in climate requires an understanding of the natural, internally generated variability of the clima ...
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Degeneration of cartilage is a major cause of chronic pain, lost mobility and reduced quality of life for millions of European citizens. From a clinical point of view treatment to achieve cartilage regeneration (hyaline) and not only repair (fibrous) remains a great challenge. No clinical therapy is available that leads to healing of cartilage defects.Current cartilage implants cannot establish th ...
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The regenerative power of a living organism is linked to the potential of its stem cells to replace the corresponding damaged tissue. Therefore organisms are as old as their stem cells. Whereas the vulnerability to cancer and chronic inflammation is associated with a decline of the immune system, the latter is in turn a sum product of interactions among hematopoietic stem cells (HSC), endothelial ...
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Kinetics for Drug Discovery (K4DD) (K4DD)

Start date: Nov 1, 2012, End date: Oct 31, 2017,

There is mounting evidence that the often ignored kinetic aspects of the interaction between a drug and its target are highly relevant for clinical success. This ignorance may be one of the reasons for the high attrition rates in drug discovery, as it has been analyzed that many recently marketed drugs had indeed improved kinetic profiles. This hindsight knowledge needs to be converted into data-d ...
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Most biopharmaceuticals (BP) currently on the market are recombinant proteins which are parenterally administered. These would benefit from more patient-friendly routes of administration. Moreover, new classes of BP (e.g. siRNA, miRNA, DARPins) with specificity for intracellular targets hold promise but await the advent of efficient delivery systems before their potential can be realised into ther ...
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Organ transplantation has emerged as the “gold standard” therapy for end-stage organ failure. Incomplete control of chronic allograft injury but also the adverse effects of long-term immunosuppression (IS) continue to challenge the long-term success of transplantation. The paradigm is shifting from increasing “net”-IS by novel drugs to the concept of minimizing long-term IS as early as possible. H ...
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Although the accurate diagnosis and prevention of coronary artery disease (CAD), acute myocardial infarction (AMI) and death is a major public health issue, risk stratification for CAD with current diagnostic tools is not properly supporting clinical decision making. RiskyCAD’s overall goal is to identify novel biomarkers for asymptomatic patients in high risk of major coronary events, and develop ...
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Acquired immune deficiency (AIDS), tuberculosis (TB) and malaria are the primary infectious diseases causing death world wide. In addition to these pathogens, 170 million people are infected with hepatitis C virus (HCV), which leads to chronic liver disease. Because of shared routes of transmission, HCV co-infection is recognized as a major cause of morbidity and mortality among HIV-1 infected per ...
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Despite improved understanding of the links between ecosystem health, provision of ecosystem services and human well-being, further conceptual and empirical work is needed to make the ideas of ecosystem services (ESS) and natural capital (NC) operational. OpenNESS will therefore develop innovative and practical ways of applying them in land, water and urban management: it will identify how, where ...
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All Rights Reserved? Barriers towards EUropean CITIZENship (BEUCITIZEN)

Start date: May 1, 2013, End date: Apr 30, 2017,

The European Court of Justice expects European citizenship to become the fundamental status of nationals of the Member States. It ‘lies at the heart of the European integration process’. The treaties, legislation, and case law have given Europeans an increasing number of rights. Yet the European Commission complains that these remain underused. Therefore, it has included in FP7 a call for a large- ...
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Research accelerators are facing important challenges that must be addressed in the years to come: existing infrastructures are stretched to all performance frontiers, new world-class facilities on the ESFRI roadmap are starting or nearing completion, and strategic decisions are needed for future accelerators and major upgrades in Europe.While current projects concentrate on their specific objecti ...
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Supporting Low-cost Intervention For disEase control (SUPPORTING LIFE)

Start date: May 1, 2013, End date: Apr 30, 2017,

In developing countries, most of the 11 million deaths per year of children under the age five years occur in areas where adequate medical care is not available. In Malawi the under-five mortality rate is 133 per 1,000 live births. First-level health facilities - the closest health care services available to most sick children in developing countries are generally run by local medical physicians.T ...
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The aim of CASyM is a combined large scale effort to sustainably implement Systems Medicine across Europe. For that purpose CASyM will function as a managing and coordinating platform in bringing together a critical mass of relevant European stakeholders such as Systems Biology scientists, clinicians, programme managers, industry/SMEs as well as healthcare providers and patient organizations. The ...
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FastPass will establish and demonstrate a harmonized, modular approach for Automated Border Control (ABC) gates. FastPass brings together key players of the entire ABC value chain - system and component producers, research institutions, governmental authorities and end-users.The development of a harmonized ABC gate will be accomplished with continuous end-user involvement. The entire innovation pr ...
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Developing robust, reproducible, interoperable and collaborative hyper-models of diseases and normal physiology is a sine qua non necessity if rational, coherent and comprehensive exploitation of the invaluable information hidden within human multiscale biological data is envisaged. Responding to this imperative in the context of both the broad Virtual Physiological Human (VPH) initiative and the ...
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Engine Breakthrough Components and Subsystems (E-BREAK)

Start date: Oct 1, 2012, End date: Mar 31, 2017,

Future aero engines will need to be more efficient and contribute to the reduction on environmental impact of air transportation. They must reach some standards of performance by reducing emissions and creating some savings on operation costs.EIMG consortium has launched since several years some initiatives to develop future engines in the frame of the European Committee research programmes.Within ...
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Enhancing Knowledge for Renewed Policies against Poverty (NOPOOR)

Start date: Apr 1, 2012, End date: Mar 31, 2017,

NOPOOR aims to build new knowledge on the nature and extent of poverty in developing countries to provide policymakers with a broader understanding of poverty. We believe that poverty cannot be tackled without a comprehensive approach. We know that poverty is a multidimensional phenomenon, but NOPOOR will explore new and uncharted dimensions. It is not just a picture of poverty, but also an unders ...
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VPH Dementia Research Enabled by IT (VPH-DARE@IT)

Start date: Apr 1, 2013, End date: Mar 31, 2017,

The DementiA Research Enabled by IT project responds to the European Parliament's 2011 resolution for a European Initiative on Alzheimer's disease and other dementias, and the EU Year of the Brain 2014 Initiative. It delivers the first patient-specific predictive models for early differential diagnosis of dementias and their evolution. Its mechanistic/phenomenological models of the ageing brain ac ...
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The World Meteorological Organization (WMO) sponsored the Global Framework on Climate Services (GFCS) where the need for actionable climate information for periods from several months up to several years for economic, industrial and political planning has been expressed. However, progress in seasonal forecasting has been slow and decadal forecasting is still incipient. At the same time, new model ...
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The target of the Smartonics project is the development of Pilot lines that will combine smart technologies with smart nanomaterials for the precision synthesis of Organic Electronic (OE) devices.The Smartonics objectives are:1.Development of smart Nanomaterials for OEs (polymer & small molecule films, plasmonic NPs and super-barriers) by process and computational modeling optimization.2.Developme ...
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Cardiovascular disease (CVD) constitutes a major and increasing health burden in developed countries. The prediction is that the prevalence of these conditions will increase by ~60% over the next 20 years. Therefore, the development of novel treatments for patients with CVD becomes more and more urgent. Oxidative stress is an important molecular contributor to the pathogenesis of CVD. However, ox ...
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The ability of financial markets to bear risk is central to economic welfare and stability. Growth and economic wellbeing is inhibited if financial markets are unable to transfer resources efficiently from the suppliers of liquidity to entrepreneurs. However, this proper functioning of financial markets has been distorted by levels of volatility considerably in excess of those implied by fundament ...
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MAILPAN (MAcroencapsulation of PANcreatic Islets) is a prototype of bioartificial pancreas usable in the human designed to treat type 1 diabetic patients. The prototype was developed along different stages since 1996 and led to the creation of the SME called Defymed in 2011. Next step is now to bring the prototype to the pre-clinical and clinical phases necessary to the ensuing commercialization o ...
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"This project seeks to recover the processes by which religious beliefs and identities were defined through interreligious interaction and debate in the religious culture of a broader social base in the eastern Mediterranean (6-8th centuries AD) through examination of a neglected, unconventional corpus of medieval Greek, Syriac and Arabic literature of debate and disputation (consisting of collect ...
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The main goal of the ENHANCE project is to develop and analyse new ways to enhance society’s resilience to catastrophic natural hazard impacts, by providing new scenarios and information in selected hazard cases in close collaboration with stakeholders, and by contributing to the development of new multi-sector partnerships (MSPs) to reduce or redistribute risk. Innovation in MSPs is essential, a ...
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Training network for next generation vaccinologists (VACTRAIN)

Start date: Nov 1, 2012, End date: Oct 31, 2016,

Vaccines are the most cost-effective health interventions available (WHO). The impact of vaccination on the health of the world’s population cannot be overstressed. Vaccinolgy is the multidisciplinary discipline of developing vaccine interventions it combines knowledge from basic sciences, medical sciences, public health and social sciences. Ideally a vaccinologists would be able to have a general ...
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ESTEEM2 is an integrated infrastructure of electron microscopy facilities providing access for the academic and industrial research community in the physical sciences to some of the most powerful characterization techniques available at the nanoscale. Transnational access to ESTEEM2 centres is obtained through a transparent, simple peer review process based on merit and scientific priorities. Serv ...
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Health-related claims and symbols may be potentially influential in supporting informed choice, furthering healthier consumer food choices, and strengthening competitiveness of the European food industry in bringing about food products that support a healthier lifestyle. However, current insights into how health symbols and claims are understood and used in real-world shopping situations are limit ...
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It has long been understood that genes contribute to phenotypes that are then the basis of selection. However, the nature and process of this relationship remains largely theoretical, and the relative contribution of change in gene expression and coding sequence to phenotypic diversification is unclear. The aim of this proposal is to fuse information about sexually dimorphic phenotypes, the mating ...
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The Go-Smart project will build a generic open-source software simulation environment for planning of image guided percutaneous Minimally Invasive Cancer Treatment (MICT). MICT includes radiofrequency ablation (RFA), cryoablation, microwave ablation (MW), transarterial chemoembolisation (TACE), brachytherapy (BT), and prospectively, irreversible electroporation (IRE). Beside of TACE each type of M ...
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