Search for European Projects

27 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Beta Cell Therapy in Diabetes (BETACELLTHERAPY)

Start date: Jan 1, 2010, End date: Jun 30, 2015,

Type 1 diabetes is a serious chronic disease with major health risks and heavy burden on patients and society. It is caused by massive immune-mediated loss of insulin-producing beta cells in the pancreas that can so far not be locally corrected. A cellular allotransplant in the liver can install a new beta cell mass but the size is insufficient and the procedure faces limitations of donor shortage ...
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 18

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Dissecting the discrete steps of mitochondrial fusion (MITOFUSION)

Start date: Apr 1, 2011, End date: Mar 31, 2015,

Mitochondria are not single isolated organelles but constitute a real network comparable to the Endoplasmic Reticulum or the Golgi apparatus. In wild type conditions, this network adopts a tubular morphology that is conditioned by active and constant processes of fission and fusion of mitochondrial membranes.Unlike other organelles, fusion of mitochondrial membranes is not catalyzed by SNAREs but ...
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 1

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Circuit and Cavity Quantum Electrodynamics (CCQED)

Start date: Jan 1, 2011, End date: Dec 31, 2014,

This network will bridge two very active disciplines in physics, namely the quantum electrodynamics of atoms or ions strongly interacting with light in resonators, and the emerging field of solid-state superconducting circuit quantum electrodynamics. Advanced techniques will be developed jointly with industry partners for the manipulation of a deterministic number of particles - atoms, ions or art ...
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 13

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Verification for heterogeneous Reliable Design and Integration (Verdi)

Start date: Sep 1, 2011, End date: Aug 31, 2014,

Systems of Systems (SoS) are heterogeneous whereby the functionality more and more rely on the interaction and interoperability between the analogue/mixed-signal (AMS), digital electronics, software and other physical domains.To achieve the required reliability, robustness and quality of SoS, mastering the heterogeneous behaviour across domains is the most essential part during the development pro ...
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 8

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Future Internet testbeds/experimentation between BRazil and Europe - EU (FIBRE-EU)

Start date: Jun 1, 2011, End date: Jul 31, 2014,

In the last two decades networks, and especially the Internet, have become part of the critical infrastructure of governments, businesses, homes and schools. The current Internet architecture, designed about 30 years ago, has suffered many extensions in recent years, to include new functionalities, which were unforeseen in the original design. Many network experts now consider it is necessary to u ...
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 9

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Virtual Biodiversity Research and Access Network for Taxonomy (ViBRANT)

Start date: Dec 1, 2010, End date: Nov 30, 2013,

Biodiversity science brings information science and technologies to bear on the data and information generated by the study of organisms, their genes, and their interactions. ViBRANT will help focus the collective output of biodiversity science, making it more transparent, accountable, and accessible. Mobilising these data will address global environmental challenges, contribute to sustainable dev ...
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 20

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Exploiting Gram-negative cell division targets in the test tube to obtain anti-microbial compounds (DIVINOCELL)

Start date: Mar 1, 2009, End date: Aug 31, 2013,

The DIVINOCELL project will identify novel Gram-negative targets by exploiting the components of the divisome, their activities and interactions. It will also design selective assays for screening and will obtain a new class of antimicrobials: compounds to block bacterial division. New medicines to attack Gram-negative pathogens will decrease the burden of infectious disease and have a highly ben ...
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 12

 FINISHED 

Gamma ray astronomy and the origin of galactic cosmic rays (GAMMA)

Start date: Sep 1, 2010, End date: Aug 31, 2013,

"Diffusive shock acceleration operating at expanding supernova remnant shells is by far the most popular model for the origin of galactic cosmic rays. Despite the general consensus received by this model, an unambiguous and conclusive proof of the supernova remnant hypothesis is still missing. In this context, the recent developments in gamma ray astronomy provide us with precious insights into th ...
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 1

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Exploring Structure-Function Relationship of Enzymes at Single Molecule Level: Fluorescence and Force Spectroscopy (SMS Enzyme)

Start date: May 14, 2010, End date: Jun 1, 2013,

The relation between structure and functions is a central topic in enzymology. I propose to study that question at the single molecule level employing a novel optical and force spectroscopy. The enzyme will be linked to a glass surface employing PEG-Biotin-Streptavidin interaction. The location of a single enzyme will be determined by a dye attached to it. The substrate of the reaction, while bein ...
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 1

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How does plate tectonics work: From crystal-scale processes to mantle convection with self-consistent plates (CRYSTAL2PLATE)

Start date: Apr 1, 2009, End date: Mar 31, 2013,

"CRYSTAL2PLATE is a coherent training and career development platform for early stage and experienced scientists in Geodynamics. It involves 6 European research teams internationally recognized for their excellence in complementary fields of Earth Sciences, 2 high-technology SME, and 2 multinational companies in the oil and gas industry. It places emphasis in experience-based training through cro ...
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 8

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MAGNETIC NANOCONTAINERS FOR COMBINED HYPERTHERMIA AND CONTROLLED DRUG RELEASE (MAGNIFYCO)

Start date: Sep 1, 2009, End date: Feb 28, 2013,

The aim of this project is the assembly and the fabrication of a new generation of multifunctional nanostructures for performing combined hyperthermia and controlled drug release, specifically targeted to cancer cells. The “magnetic nanocontainers” we intend to develop can perform at the same time cell recognition, hyperthermia treatment, and, as a consequence of the heat and /or cell environment ...
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 11

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MULTI-SCALE COMPLEX FLUID FLOWS and INTERFACIAL PHENOMENA (MULTIFLOW)

Start date: Jan 1, 2009, End date: Dec 31, 2012,

"Understanding and controlling of interfacial phenomena in multiphase fluid dynamics remains one of the main challenges at the crossroad of Mathematics, Physics, Chemistry and Engineering. Examples include film flows, spreading and dewetting of (complex) liquids including suspensions, polymer solutions, liquid crystals, colloids and biofluids. Such systems are central for technological advances in ...
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 10

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Characterization and quantitative modeling of DNA mismatch repair and its role in the maintenance of genomic stability and cancer avoidance (mismatch2model)

Start date: Nov 1, 2008, End date: Oct 31, 2012,

Mismatch2model: Characterization and quantitative modeling of DNA mismatch repair and its role in the maintenance of genomic stability and cancer avoidance DNA mismatch repair (MMR) plays a crucial role in the maintenance of genomic stability. In both bacteria and eukaryotes, the loss of mismatch repair gives rise to a mutator phenotype. In hereditary non-polyposis colon cancer (HNPCC) families, ...
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 6

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Towards the deterministic modelling of immiscible flows in porous media: Mesoscale simulations and Experimental verification (REAL PORE FLOWS)

Start date: Sep 1, 2010, End date: Aug 31, 2012,

"Immiscible two-phase flow in macroporous materials is a subject of significant applied and scientific interest. It is encountered in a series of environmental and energy-related processes such as soil remediation, enhanced oil recovery from fractured petroleum reservoirs, geothermal processes, CO2 sequestration etc. The study and optimization of such processes requires the development of rigorous ...
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 1

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Defects in two dimensional field theories (D2DFT)

Start date: Sep 1, 2010, End date: Aug 31, 2012,

"The aim of this proposal is to study aspects of one dimensional defects in two dimensional field theories. One aspect is the relation of a certain class of defects, Wilson loops, to the integrable structure of Wess-Zumino-Witten models and coset models. Through the use of quantum groups, it should be possilbe to quantize these classical defects and describe exactly in a universal way a large clas ...
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 1

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Quantum Nanoelectromechanical Systems (QNEMS)

Start date: Sep 1, 2009, End date: Aug 31, 2012,

In this project, we will investigate the quantum properties of nanoscale mechanical resonators. Suspended structures will be made of Al, SiN, GaAs, carbon nanotubes, and photonic crystals, covering frequencies in the MHz and GHz range. The vibrations will be excited by electrical means. To overcome the thermal noise, cooling of the low-frequency resonators will be performed. We will use two coolin ...
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 8

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Dissecting the new “platform-binding site” on the bacterial ribosome. Role of particular ribosomal proteins in regulating translation initiation in bacteria (PBS)

Start date: Feb 1, 2010, End date: Jan 31, 2012,

"Recent X-ray crystallographic and cryo-electron microscopy data indicate that structured mRNAs bind to the bacterial ribosome at an early step of translation initiation, to a newly characterised ribosomal site located at the “platform” of the small ribosomal subunit (the “platform-binding” site or PBS). In a second step, the mRNAs are supposed to unfold and to migrate to the P-site to interact wi ...
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 1

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High Dimensional Entangled Systems (HIDEAS)

Start date: Oct 1, 2008, End date: Jan 31, 2012,

HIDEAS aims at a breakthrough in the information capacity of Quantum Communication (QC), well beyond the standard single-mode approach, by exploiting the intrinsic multi-modal and multivariate character of the radiation field. Our long term vision is that of a broadband Quantum Communication, where all the physical properties of the photons are utilized to store information. Working at the quantum ...
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 11

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The power of quantum computers (QUCO)

Start date: Jul 1, 2008, End date: Nov 30, 2011,

Quantum computation has been put forward as a way to overcome current computational limits, by exploiting the quantum properties of nature. It is an interdisciplinary area at the interface of physics and computation. Since Shor's groundbreaking discovery in 1994 that a quantum computer can factor numbers efficiently, strong, steady advances have been made in understanding the advantages of quantum ...
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 2

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Dark Matter and Stars in the Dark Ages (DAMiDA)

Start date: Nov 12, 2009, End date: Nov 11, 2011,

The possibility that the first stars in the universe may be powered by dark matter annihilation rather than nuclear fusion has been recently proposed in the literature. This intriguing phenomenology defines a new field, in which particle dark matter properties affect the characteristics of astrophysical populations in the young universe. In DAMiDA we propose a thorough approach to the problem: ste ...
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 1

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"The process of professionalization in European science, 1789-1850" (PROSCIENCE)

Start date: Nov 1, 2009, End date: Oct 31, 2011,

"The modern science was born in Europe at the beginning of the seventeenth century, but it was not until the middle of the nineteenth century that the scientific research became “professionalized” as we know it today. Such a process of “professionalization” was a milestone in the development of the European intellectual heritage and made Europe the world leader in the production of knowledge. Its ...
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 1

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Spinor Bose-Einstein Condensates for many-particle entanglement (SCoPE)

Start date: May 1, 2009, End date: Apr 30, 2011,

Since the early days of quantum theory and even more since development of the field of quantum computation, it is well established that correlation and entanglement are fundamental in quantum mechanics and a remarkable effort is on the way to better understand these concepts, both from the theoretical and the experimental point of view. In this proposal a series of new experiments devoted to the s ...
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 1

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Preparing for the construction of the Digital Research Infrastructure for the Arts and Humanities (PREPARINGDARIAH)

Start date: Sep 1, 2008, End date: Feb 28, 2011,

The grand vision for the Digital Research Infrastructure for the Arts and Humanities (DARIAH) is to facilitate access to research material for the humanities and for supporting the preservation of digital heritage material in Europe. DARIAH connects information users (researchers), information managers and information providers. It gives them a technical framework that enables enhanced data sharin ...
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 15

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Black Holes, Superstrings, and Holography (BlackHoleHologram)

Start date: Oct 1, 2008, End date: Sep 30, 2010,

"This project aims to understand certain quantum aspects of black hole physics, in particular its entropy and the degrees of freedom associated with the horizon. The many states in which a black hole can exist can be understood through a ""hologram"" living in one dimension less than the black hole. This idea of a hologram has proved to be very fruitful in recent work in string theory. Our work a ...
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 1

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Quantum phases of a two-dimensional Bose gas (FLATLAND)

Start date: Jun 1, 2008, End date: May 31, 2010,

"The proposed project aims at the experimental study of two-dimensional (2D) quantum degenerate Bose gases. In a first stage we will explore the coherence properties of the gas below the critical temperature of the Kosterlitz-Thouless transition. One of our objectives is to reveal the superfluid character of the gas. For this purpose we will rotate the trapped cloud to excite particular collective ...
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 1

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Conditional Measurements in Quantum Optics for Application in Quantum Information (QuantManip)

Start date: Jun 1, 2008, End date: May 31, 2010,

This project points to the experimental realization of suitably designed optical states for quantum communications uses. The quantum state will be conveniently manipulated by its projection on another one of predictable properties. The process will be realized by means of a conditional measurement performing a post-selection of the beam by monitoring a suitable observable on a fraction of it. The ...
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 1

 FINISHED 

Cytosolic iron metabolism in unicellular eukaryotic pathogens (patho iron)

Start date: Aug 4, 2008, End date: Feb 3, 2010,

Iron is an essential nutrient for virtually all living organisms and host iron availability plays a critical role in the host–pathogen relationship. Without effective mechanisms for acquisition, transport and utilization of iron, no organism especially parasites with high iron requirements, can survive. However, our knowledge about intracellular iron metabolism in eukaryotic pathogenic microorgani ...
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 1