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Arginine vasopressin and ion transporters in the modulation of brain excitability during birth and birth asphyxia seizures (PRESSBIRTH)
Start date: Feb 1, 2014, End date: Jan 31, 2019,
A transient period of asphyxia in the newborn is an obligatory part of normal parturition. A more prolonged disturbance in cerebral blood supply is a major cause of neonatal seizures. Current therapies of birth asphyxia seizures are ineffective and the underlying mechanisms are unknown.Our recent landmark work on a rat model of birth asphyxia showed that asphyxia is followed by brain alkalosis, wh ...
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