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Sorting out host recognition of fungal infection (FUNGISORT)

Start date: Jun 1, 2014, End date: May 31, 2016,

The fungus Candida albicans is a common cause of human infection with serious morbidity, but the organism is also a commensal yeast that is part of the normal gut microbiota. It is becoming increasingly clear that the composition of the microbiome plays an important role in health and disease. For instance, recently it was shown that commensal fungi in the gut can contribute to the severity of col ...
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Bacterial pathogens often secrete proteins into their environment to institute infection of eukaryotic host cells. Common virulence-associated protein secretion machineries are the well studied type III and IV systems that facilitate proteins to associate with and translocate into eukaryotic cells. The principal bacterial food-borne pathogen Campylobacter jejuni and related species lack these syst ...
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