4 European Projects Found
Searched on 125080 European Projects
FINISHED
Clinical development of a dendritic-cell vaccine therapy for acute myeloid leukaemia (AML-VACCiN)
Start date: Jan 1, 2016, End date: Mar 31, 2020,
Eradicating minimal residual disease (MRD) in patients with acute myeloid leukaemia (AML) is an area of high unmet medical need. AML is a deadly rare disease that affects both children and adults. Approximately 45% of younger AML patients who are treated will be cured, and in older patients (>60 years of age), 85% will relapse and die within 2 years.Immunotherapy has great potential for treating M ...
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12
Partners Participants
FINISHED
Cancer Vaccine development for Hepatocellular Carcinoma (HepaVac)
Start date: Sep 1, 2013, End date: Aug 31, 2018,
"Hepatocellular carcinoma (HCC) is the most common primary liver cancer and accounts for about 6% of all new cancer cases worldwide. Given the lack of available effective treatments, the overall prognosis for HCC patients is poor, with a dismal 5-year survival of 5-6%. The main goal of this proposal is to develop a therapeutic cancer vaccine aiming at improving clinical outcome in early-stage HCC ...
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10
Partners Participants
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Glioma Actively Personalized Vaccine Consortium (GAPVAC)
Start date: Nov 1, 2012, End date: Jan 31, 2017,
"Glioblastoma (GBM) is a rare (2-3 incidences in 100,000) and fatal disease. Each year, approximately 13,000 new cases of GBM are diagnosed in Europe. The 5-year survival rate of this highly aggressive tumor entity under conventional therapy is less than 6%. Currently available therapeutic options neglect the individuality of each patients’ disease and only temporarily influence tumor progression ...
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13
Partners Participants
FINISHED
IMmune MOdulating strategies for treatment of MErkel cell Carcinoma (IMMOMEC)
Start date: Jan 1, 2012, End date: Dec 31, 2016,
"Merkel cell carcinoma (MCC) is a highly aggressive, often lethal neuroendocrine cancer of the skin associated with the recently discovered, common Merkel cell polyomavirus (MCV). With an incidence of 0.44 per 100,000 MCC is a very rare cancer. Notably, however, although MCC is 40 times less common than malignant melanoma, MCC has a dramatically higher mortality rate than melanoma rendering MCC to ...
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