Search for European Projects

30 European Projects Found

Searched on 125080 European Projects

 FINISHED 

SIMVASTATIN AND RIFAXIMIN AS NEW THERAPY FOR PATIENTS WITH DECOMPENSATED CIRRHOSIS (LIVERHOPE)

Start date: Jan 1, 2017, End date: Dec 31, 2021,

Liver cirrhosis is a very common chronic disease and one of the leading causes of death in European. Moreover, cirrhosis has a marked impact in patients quality of life and represents a major burden for health systems. Treatment of cirrhosis is currently based on symptomatic management of complications and has not changed substantially in the last 20 years. There is an unmet need for therapies tha ...
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 18

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Comorbid Conditions of Attention deficit / hyperactivity disorder (CoCA)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

Understanding mechanisms underlying comorbid disorders poses a challenge for developing precision medicine tools. Psychiatric disorders are highly comorbid, and are among the last areas of medicine, where classification is driven by phenomenology rather than pathophysiology. We will study comorbidity between the most frequent psychiatric conditions, ADHD, mood/anxiety, and substance use disorders, ...
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 17

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A Phase Ib/II study of MEK1/2 inhibitor PD-0325901 or MEK-162 with cMET inhibitor PF-02341066 in RASMT and RASWT (with aberrant c-MET) Colorectal Cancer Patients (MERCURIC)

Start date: Dec 1, 2013, End date: Nov 30, 2020,

Colorectal cancer (CRC) is the 3rd most common cancer in Europe, and with approximately 200,000 deaths per year, it remains the 2nd most common cause of cancer death. More than half of all CRC patients develop distant metastases and have 5-year overall survival (OS) of less than 5% because of ineffective treatments. Increased understanding of cancer biology, coupled with the implementation of “omi ...
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 13

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REgenerative Stem cell therapy for STroke in Europe (RESSTORE)

Start date: Sep 1, 2015, End date: Aug 31, 2020,

Stroke is the second leading cause of death in the world population. When not fatal, stroke often results in disability, due to motor and cognitive impairments, and secondary health problems affecting not only patients but also their families. Building on emerging preclinical and pilot clinical evidences, RESSTORE will focus on the clinical assessment of regenerative cell therapy to improve stroke ...
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 29

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Brain injury and trauma monitoring using advanced photonics (BitMap)

Start date: Jan 1, 2016, End date: Dec 31, 2019,

Our vision is to develop a suite of standardised non-invasive devices that will provide essential information about brain health in neurocritical care and neuromonitoring, with a particular emphasis on 1. traumatic brain injury: the “silent epidemic of the third millennium” and 2. hypoxia in newborn children. Survivors present permanent neurological conditions that have a profound impact on the qu ...
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 11

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Clinical evaluation of carbons of controlled porosity as a new therapeutic for the treatment of liver cirrhosis and non-alcoholic fatty liver disease. (CARBALIVE)

Start date: May 1, 2015, End date: Oct 31, 2019,

Chronic liver disease affects about 29-million Europeans accounting for about 170,000 deaths at a cost of around €15.8bn. This chronic non-communicable disease is increasing at an alarming rate due to increasing European obesity, alcohol use and ageing. The three main causes of the disease; alcohol, fatty liver and viral hepatitis are amenable to prevention and treatment. Gut-derived endotoxins an ...
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 15

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Deciphering PI3K biology in health and disease (Phd)

Start date: Nov 1, 2015, End date: Oct 31, 2019,

The Phosphoinositide 3-kinase (PI3K) pathway is at the core of multiple fundamental biological processes controlling metabolism, protein synthesis, cell growth, survival, and migration. This inevitably leads to the involvement of the PI3K signalling pathway in a number of different diseases, ranging from inflammation and diabetes to cancer, with PI3K pathway alterations present in almost 80% of hu ...
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 11

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Mastering skills in the training Network for attention deficit hyperactivity and autism spectrum Disorders (MiND)

Start date: Jan 1, 2015, End date: Dec 31, 2018,

Attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) are frequent, chronic and highly heritable neurodevelopmental disorders. Despite their societal importance, progress in understanding disease biology has been slow and no curative treatment options are available.The pan-European training network MiND aims to educate a new generation of researchers in the field of n ...
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 12

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Aggression subtyping for improved insight and treatment innovation in psychiatric disorders (AGGRESSOTYPE)

Start date: Nov 1, 2013, End date: Oct 31, 2018,

Aggression is a basic physiological trait with important roles throughout evolution, both in defence and predation. When expressed in humans in the wrong context, aggression leads to maladjustment, social impairment and crime. Despite this, knowledge about aggression aetiology is limited and current treatment strategies are insufficient. Contingent to a subdivision into impulsive and instrumental ...
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 27

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Raising the Quality of Teacher Education Programmes in Palestine

Start date: Oct 15, 2015, End date: Oct 14, 2018,

Despite numerous initiatives to upgrade the quality of the teaching profession in Palestine in recent years, there have been none that have led to a complete holistic reform of BA Primary Education degree programmes to reflect international practice. This project addresses this need by adopting a systemic, holistic approach to quality reform of all elements of BA Primary Education degree programm ...
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 6

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Development of Health Informatics integrated curricula in Computing and Health-oriented undergraduate degrees

Start date: Oct 15, 2015, End date: Oct 14, 2018,

The HiCure project seeks to build capacities to develop an integrated curricula in Health Informatics as pathways within the undergraduate degrees of the faculties of Health and Information Technology, using a student-centred adaptive learning approach based on the bologna processes. It aims to develop two pathways, integrated within the current curricula, to bring continuity and achieve harmony ...
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 8

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Creating medically-driven integrative bioinformatics applications focused on oncology, CNS disorders and their comorbidities (MedBioinformatics) (MedBioinformatics)

Start date: May 1, 2015, End date: Apr 30, 2018,

Progress in biomedical research and healthcare requires profiting from the huge amount of data and knowledge that are generated. However, most of the potential users have no means to efficiently exploit this wealth of information. Up to now, many of the efforts done for developing bioinformatics methods and applications have not produced the expected societal impact for different reasons, includin ...
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 13

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European Training in Neural Regulation of Intestinal Function (NeuroGut)

Start date: Feb 1, 2014, End date: Jan 31, 2018,

"Neurogastroenterology is a new and emerging medical/scientific subspecialty that currently has no formal training opportunities in medicine and related disciplines. It includes basic science aspects (neurophysiology, neurobiology, neuropsychology, psychophysiology) and clinical aspects (gastroenterology, neurology, internal medicine, surgery, psychology, psychosomatic medicine) of the neural cont ...
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 12

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Early Prevention of Diabetes Complications in people with Hyperglycaemia in Europe (E-PREDICE)

Start date: Jan 1, 2012, End date: Dec 31, 2017,

"Background: A significant proportion of pre-diabetics, show macro and micro vascular complications associated with hyperglycaemia. Although many trials have demonstrated the efficacy of lifestyle and pharmaceutical interventions in diabetes prevention, no trial has evaluated the extent to which mid- and long-term complications can be prevented by early interventions on hyperglycaemia.Aims: To ass ...
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 37

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Framework to respond to regulatory needs of future nanomaterials and markets (FutureNanoNeeds)

Start date: Jan 1, 2014, End date: Dec 31, 2017,

Rapidly developing markets such as green construction, energy harvesting and storage, advanced materials for aerospace, electronics, medical implants and environmental remediation are potential key application targets for nanomaterials. There, nanotechnology has the potential to make qualitative improvements or indeed even to enable the technology. Impacts range from increased efficiency of energy ...
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 26

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Assessment and mitigation of nano-enabled product risks on human and environmental health: Development of new strategies and creation of a digital guidance tool for nanotech industries (GUIDENANO)

Start date: Nov 1, 2013, End date: Apr 30, 2017,

The main objective of GUIDEnano is to develop innovative methodologies to evaluate and manage human and environmental health risks of nano-enabled products, considering the whole product life cycle. A strategy to identify hot spots for release of nanomaterials (NMs) will be followed by decision trees to guide on the use of (computational) exposure models and, when necessary, design of cost-effecti ...
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 34

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Anti-Biopharmaceutical Immunization:Prediction and analysis of clinical relevance to minimize the risk (ABIRISK)

Start date: Mar 1, 2012, End date: Feb 28, 2017,

The ABIRISK project provides an integrated approach to the study of immunization against biopharmaceuticals, bringing together a unique panel of experts from different disciplines. ABIRISK will involve many of the European leaders in rheumatology, gastroenterology, hemophilia and multiple sclerosis, caring for ~30,000 patients treated with biopharmaceuticals, with ~10,000 additional patients recru ...
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 39

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European multicentre, randomised, phase III clinical trial of hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke (EuroHYP-1)

Start date: Feb 1, 2012, End date: Jan 31, 2017,

The consortium led by UKER and EuroHYP, the European Stroke Research Network for Hypothermia, proposes a large, multicentre clinical trial which will assess mild hypothermia as a novel treatment for ischemic stroke.Stroke is the second cause of death world-wide and the second cause of lost disability-adjusted life years in high-income countries. Stroke incidence rises exponentially with age, so it ...
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 38

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OncoTrack - Methods for systematic next generation oncology biomarker development (ONCOTRACK)

Start date: Jan 1, 2011, End date: Dec 31, 2016,

We propose here an exhaustive analysis of the genome, exome, methylome and transcriptome of primary tumours and metastases from patients with colon carcinoma, based on a combination of deep sequencing and chip based techniques. Dependent on their availability, we shall also perform analyses of tumor stem cells, circulating tumor cells, free tumor DNA in serum and xenografts derived from the same p ...
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 22

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A European Platform for Translational Cancer Research (EUROCANPLATFORM)

Start date: Jan 1, 2011, End date: Dec 31, 2016,

Europe has a number of advantages as regards developing translational cancer research, yet there is no clear European strategy to meet the increasing burden posed by cancer. The FP6 Eurocan+Plus project analysed the barriers underlying the increasing fragmentation of cancer research and stressed the need to improve collaboration between basic/preclinical and comprehensive cancer centres (CCCs), in ...
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 29

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Rational Therapy for Breast Cancer: Individualized Treatment for Difficult-to-Treat Breast Cancer Subtypes (RATHER)

Start date: Jan 1, 2011, End date: Dec 31, 2016,

"Cancer genotyping has identified a number of correlations between mutations in specific genes and responses to targeted anti-cancer drugs, with many mutations occurring in kinases or downstream signaling components. While there are several ongoing large-scale genome re-sequencing studies for the major cancer types, there is no systematic effort to investigate kinase mutations in distinct biologic ...
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 8

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European Consortium for the Early Treatment of Diabetic Retinopathy (EUROCONDOR)

Start date: Mar 1, 2012, End date: Jun 30, 2016,

Diabetic retinopathy (DR), the leading cause of blindness among working-age individuals in developed countries has been classically considered to be a microcirculatory disease of the retina. However, there is growing evidence to suggest that retinal neurodegeneration is an early event in the pathogenesis of DR. For this reason, it is reasonable to hypothesize that therapeutic strategies based on n ...
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 18

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Multicentre Preclinical Animal Research Team (Multi-PART)

Start date: Sep 1, 2013, End date: Aug 31, 2015,

Millions of Europeans still suffer the consequences of neurological disease, but the number of new drugs coming to market continues to fall. Reasons for the failure of stroke drug efficacy to translate from animals to clinical trials is probably best studied, but the problem is widespread. The economic and social costs of translational failure are substantial; a new approach to translational medic ...
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 12

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WINTHERapeutics: development of a systems biology method to predict efficacy of cancer drugs to optimize individualized therapeutic decision and improve clinical outcome for cancer patients (WINTHER)

Start date: Mar 1, 2013, End date: Feb 28, 2015,

Relevance: WINTHER project focuses on the development and validation, in 24 months, of industry supported new tools and computational methods, to predict efficacy of drugs in cancer patientsCurrent medical needs: Selection of cancer targeted therapies based on molecular abnormalities (mutations /amplifications/ translocations) benefit today only to 10-40% of patients. For the remaining majority, ...
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 12

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Modelling and predicting sensitivity to targeted therapies in colorectal cancers (COLTHERES)

Start date: Jan 1, 2011, End date: Dec 31, 2014,

Effective and long term treatment of cancer is now in sight, but will ultimately require an increasingly ‘personalised’ approach where the ‘right’ combination of drugs will be administered to the ‘right’ patients, based on a detailed understanding of their genetic background and their co-associated sensitivity or resistance ‘biomarkers’. Efforts are specifically required to identify validated risk ...
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 11

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United Europeans for the Development of Pharmacogenomics in Multiple Sclerosis (UEPHA-MS)

Start date: Sep 15, 2008, End date: Sep 14, 2012,

"Multiple sclerosis (MS) is a chronic inflammatory, disabling disease of the central nervous system. Recent studies suggest that over the last 50 years a disproportional increase in incidence of MS in women has taken place. The lifetime costs of MS exceed 1.5 million € per case in the UK, and are likely to be similar in other European countries. There is no definitive cure for MS. Immunomodulatory ...
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 12

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Central Offices Responsible for the Integration at Home of Internationalisation as Assurance of quality in the Meda region

Start date: Jan 15, 2010,

The project comes as result of the participation of 5 of the 6 partner universities in the programme Erasmus Mundus External Cooperation Windows. Given the importance to create structural measures that sustain the exchange of mobilities and facilities joint ventures, degrees and programmes this project proposal attempts to construct those pillars that will strengthen the harmonisation of higher ed ...
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 16

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L03 - South Med. - oPt/Israël

Start date: Jul 15, 2009,

Lot3.emecw.com is a partnership of 20 European, Israeli and Palestinian institutions for higher education, led by Vrije Universiteit Brussel (VUB). Its aim is to stimulate academic mobility at all levels (undergraduate, master, doctoral, postdoctoral and academic staff) from Israel and Palestine to Europe and vice versa.VUB and its European partners have extensive experience in academic cooperati ...
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 39

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Strengthening University-Enterprise linkages in Palestine

Start date: Oct 15, 2012,

Enhancing cooperation between Higher Education Institutions (HEIs) and industry has become a critical issue to respond to the challenges of increasing employment opportunities and socio-economic growth (in Europe, this was already highlighted under the ‘Lisbon Strategy 2000’ and is now reinforced under the ‘Europe 2020 Strategy’).While there is a global economic deadlock, the situation is particul ...
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 11

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EMII A2 S1L3B EMECW Lot 3

Start date: Oct 18, 2010,

Lot 3b is a partnership of 16 European and Palestinian universities, led by the Vrije Universiteit Brussel (VUB). Its aim is to stimulate academic mobility at ali levels and both ways, but especially at PhD level since the project will support the Palestinian universities in setting up doctoral programmes. VUB and most of the European partners have extensive experience in academic cooperation with ...
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 15