1 European Projects Found
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Genomic screens to identify and characterize mechanisms of mycobacterial killing by Macrophages (MACROPHAGE GENOMICS)
Start date: Oct 1, 2007, End date: Sep 30, 2009,
Non-pathogenic mycobacteria are efficiently phagocytosed by macrophages and killed within phagosomes by acid hydrolases, reactive nitrogen intermediates, and likely other still unidentified factors that are part of the macrophage pro-inflammatory response. In contrast, pathogenic mycobacteria such as M. tuberculosis survive and grow within phagosomes by blocking macrophage pro-inflammatory respons ...
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