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Over 40 European Projects Found

Searched on 125080 European Projects

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Due to lack of targeted interventions, compliance issues, insufficient effect sizes and a high non-responder rate to currently available interventions, there is an urgent need to develop innovative and new interventions for chronic paediatric neuropsychiatric disorders, such as Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD). Transcranial direct current stimulati ...
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Instruct-Ultra aims to advance the scope and efficiency of implementation of Instruct and consolidate the foundations for long-term sustainability. This will be achieved through specific objectives: expand Instruct membership to new Member States and increase global links; engage new user communities; improve efficiencies in service delivery; improve data capture and management; adjust the scale a ...
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Screening for vision and hearing disorders in children has shown to be highly effective. EU-directive 16620/11 invites EU-member states to give priority to such screening programmes. Early detection and treatment of a lazy eye (prevalence 3%) prevents lifelong visual impairment. Early detection and treatment of hearing impairment (prevalence 0.15%) prevents delayed speech and language development. ...
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The proposed project “Readiness of ICOS for Necessities of integrated Global Observations” (RINGO) aims to further development of ICOS RI and ICOS ERIC and foster its sustainability. The challenges are to further develop the readiness of ICOS RI along five principal objectives: 1. Scientific readiness. To support the further consolidation of the observational networks and enhance their quality. Th ...
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MMbio will bridge the classically separate disciplines of Chemistry and Biology by assembling leading experts from academia and non-academic partners (industry, technology transfer & science communication) to bring about systems designed to interfere therapeutically with gene expression in living cells. Expertise in nucleic acid synthesis, its molecular recognition and chemical reactivity is combi ...
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Understanding mechanisms underlying comorbid disorders poses a challenge for developing precision medicine tools. Psychiatric disorders are highly comorbid, and are among the last areas of medicine, where classification is driven by phenomenology rather than pathophysiology. We will study comorbidity between the most frequent psychiatric conditions, ADHD, mood/anxiety, and substance use disorders, ...
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Cell-cell interactions at the neurovascular interface (NEUROVESSEL)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

The coordinated orchestration of cell movements is a vital process for assembling functional structures. In recent years we have learned a simplifying lesson: organ development is governed by a limited set of conserved cell-to-cell communication signaling pathways repeatedly used in different contexts. Particularly fascinating is the parallelism between the vascular and nervous systems. My lab has ...
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Endothelial long non-coding RNAs (Angiolnc)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

Endothelial cells comprise the inner cellular cover of the vasculature, which delivers metabolites and oxygen to the tissue. Dysfunction of endothelial cells as it occurs during aging or metabolic syndromes can result in atherosclerosis, which can lead to myocardial infarction or stroke, whereas pathological angiogenesis contributes to tumor growth and diabetic retinopathy. Thus, endothelial cells ...
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CHASSY will unlock the full potential of the yeasts Saccharomyces cerevisiae, Yarrowia lipolytica and Kluyveromyces marxianus as cell factories for production of high value compounds which have applications in the cosmetic, nutraceutical and white biotechnology sectors. Current cell factory strains for these classes of product are restricted to proof-of-principle levels because of limited precurso ...
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Goal-based Open-ended Autonomous Learning Robots (GOAL-Robots)

Start date: Nov 1, 2016, End date: Oct 31, 2020,

This project aims to develop a new paradigm to build open-ended learning robots called `Goal-based Open-ended Autonomous Learning' (GOAL). GOAL rests upon two key insights. First, to exhibit an autonomous open-ended learning process, robots should be able to self-generate goals, and hence tasks to practice. Second, new learning algorithms can leverage self-generated goals to dramatically accelerat ...
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HotMaps will develop, demonstrate and disseminate a toolbox to support public authorities, energy agencies and planners in strategic heating and cooling planning on local, regional and national levels, and in-line with EU policies. The toolbox will facilitate the following tasks on a spatially disaggregated level: (1) Mapping heating and cooling energy situation including renewable and waste heat ...
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 16

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Imaging the Event Horizon of Black Holes (BLACKHOLECAM)

Start date: Oct 1, 2014, End date: Sep 30, 2020,

Gravity is successfully described by Einstein’s theory of general relativity (GR), governing the structure of our entire universe. Yet it remains the least understood of all forces in nature, resisting unification with quantum physics. One of the most fundamental predictions of GR are black holes (BHs). Their defining feature is the event horizon, the surface that light cannot escape and where tim ...
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Unraveling Principles of PDZ-mediated Cell Signaling (PDZnet)

Start date: Sep 1, 2016, End date: Aug 31, 2020,

PDZnet will create an innovative European PhD training network focusing on unraveling PDZ domain-mediated signaling networks. The emphasis will be on signaling nodes essential for the development of cancer and diseases of the nervous system, conditions that affect millions of Europeans and are major societal challenges. PDZ domains are protein and lipid recognizing modules that play a central role ...
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The European Pharma industry is a major contributor to EU well-being, both in public health and economic (sales >200 billion €/year) terms. To maintain global leadership, it must respond to challenges from low-cost producers e.g. China by bringing new drug molecules to market in a streamlined, cost-effective manner. This strategy is underscored by recent initiatives of European regulators to exped ...
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Non-coding RNA in Vascular Ageing (NOVA)

Start date: Apr 1, 2015, End date: Mar 31, 2020,

Life expectancy in the European Union is rising and the prevalence of age-induced cardiovascular disease increases concomitantly. Endothelial dysfunction is a hallmark of aging in the vasculature and is the underlying cause of many cardiovascular disorders, like hypertension, acute myocardial infarction and stroke. This proposal aims to better understand the molecular mechanisms behind aging that ...
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CELTA: Convergence of Electronics and Photonics Technologies for Enabling Terahertz Applications aims to produce the next generation of researchers who will enable Europe to take a leading role in the multidisciplinary area of utilizing Terahertz technology for applications involving components and complete systems for sensing, instrumentation, imaging, spectroscopy, and communications. All these ...
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 13

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In the face of the increasing global consumption of fossil resources, photosynthetic organisms offer an attractive alternative that could meet our rising future needs as clean, renewable, sources of energy and for the production of fine chemicals. Key to the efficient exploitation of these organisms is to optimise the conversion of Solar Energy into Biomass (SE2B). The SE2B network deals with this ...
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In the ASPIRE project, whose academic and industrial beneficiaries are world leading in their complementary fields of expertise, the overarching research goal is the measurement of photoelectron angular distributions (PADs) in the “molecular frame” (MF) of systems of biological relevance. These MF-PADs can be interpreted as electron diffraction patterns, achieved by “illuminating the molecule from ...
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Self-renew and multilineage potential characterize stem cells. We have recently described that pancreas progenitor cells extracted from adult donors can be expanded long-term in vitro into 3D structures, which we have termed organoids. Pancreas organoids reproduce in vitro all the features of pancreas ductal epithelia, and have a limitless expansion potential. Thus, pancreas organoids promise t ...
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Privacy and Usabiliy (Privacy.Us)

Start date: Dec 1, 2015, End date: Nov 30, 2019,

With the rapid accumulation and processing of personal data by numerous organizations, it is of paramount importance to protect people from adverse uses of their data, while allowing them to enjoy the benefits the use of these data can possibly provide. This is the question of protecting citizens’ privacy, while enabling them to make informed decisions regarding their actions with privacy implicat ...
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Deciphering the Metabolism of Haematological Cancers (HaemMetabolome)

Start date: Oct 1, 2015, End date: Sep 30, 2019,

It has long been realised that metabolism is central to cellular development, proliferation and homeostasis. Collectively, aberrations in metabolism are now recognised as a major hallmark of cancer, opening new avenues for personalised medicine. As haematological malignancies are multi-factorial diseases, our main emphasis will be on the integration of biomedical multi-omics data and computational ...
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Endoplasmic Reticulum Stress in Health and Disease (TRAIN-ERS)

Start date: Oct 1, 2015, End date: Sep 30, 2019,

Endoplasmic reticulum (ER) stress is emerging as a common feature in the pathology of numerous diseases including cancer, neurodegenerative disorders, metabolic syndromes and inflammatory diseases. Thus ER stress represents a potential therapeutic intervention point to be exploited to develop novel therapies, diagnostic tools and markers for these diseases. However, exploitation is hampered by the ...
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An Exascale Hyperbolic PDE Engine (ExaHyPE)

Start date: Oct 1, 2015, End date: Sep 30, 2019,

Many aspects of our life, but also cutting-edge research questions, hinge on the solution of large systems of partial differential equations expressing conservation laws. Such equations are solved to compute accurate weather forecast, complex earthquake physics, hematic flows in patients, or the most catastrophic events in the universe. Yet, our ability to exploit the predictive power of these mod ...
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Die Effektivität des EU-Rechts in der Krise der Europäischen Union

Start date: Sep 1, 2016, End date: Aug 31, 2019,

The Jean Monnet – Centre of Excellence on “The Effectiveness of EU-Law in Times of Crisis” (EfEU) analyses the legal principle of effectiveness established by the European Court of Justice. The Centre explores the legal, cultural, political and economic dimensions of this principle in the context of the current crisis of the EU. The proposal builds on the successful Roadmap-Project (Jean Monnet Ce ...
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"The proposal describes a project to deliver a comprehensive evaluation of the relationship between unemployment and social stratification in Europe and North America. The project’s core goal is to provide empirical estimates of the causal impact of unemployment on four critical domains of social life, namely household incomes, demographic behaviour, educational attainment, as well as social integ ...
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Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials.iNEXT (infrastructure for NMR, EM and X-rays for Translational rese ...
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Brain barriers training (BtRAIN)

Start date: Sep 1, 2015, End date: Aug 31, 2019,

The brain barriers function to protect the central nervous system (CNS) from neurotoxic compounds. By the same traits they unfortunately block delivery of drugs to the CNS thus hindering proper diagnosis and effective treatment of neurological disorders including Alzheimer’s disease and multiple sclerosis. The unusual complexity of the brain barriers has severely hampered progress in the market of ...
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"This project aims at elucidating fundamental neural computations underlying language processing. While we have gained enormous insights into the localization of language in the brain and the temporal sequence of language processes (e.g., syntactic vs. semantic), we know very little about the actual computations underlying language processing. I propose that the framework of predictive coding can ...
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The main objective of the project is to provide a treatment of the neurological symptoms of patients with Ataxia Telangiectasia (AT), a rare progressively disabling and life-shortening genetic disease for which no therapy is currently available. To achieve this, a pivotal Phase III study will be conducted, to allow regulatory filing to obtain market authorization in EU and USA by 2019. EryDex is a ...
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Neutron cAptUres consTraIning steLlar nUcleosynthesiS (NAUTILUS)

Start date: Apr 1, 2014, End date: Mar 31, 2019,

...gion will be measured by a time-of-flight (TOF) experiment. NAUTILUS will provide a unique facility realizing the TOF technique with an ultra-short flight path at the FRANZ setup at Goethe University Frankfurt am Main, Germany. A highly optimized spherical photon calorimeter will be built and installed at an ultra-short flight path.NAUTILUS opens new horizons in the area of neutron-induced reactio ...
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MYRRHA Research and Transmutation Endeavour (MYRTE)

Start date: Apr 1, 2015, End date: Mar 31, 2019,

The Strategic Research Agenda of the EU Sustainable Nuclear Energy Technical platform requires new large infrastructures for its successful deployment. MYRRHA has been identified as a long term supporting research facility for all ESNII systems and as such put in the high-priority list of ESFRI. The goal of MYRTE is to perform the necessary research in order to demonstrate the feasibility of trans ...
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Most European Lifelong Learning (LLL) policies have been designed to create economic growth and, at the same time, guarantee social inclusion (EC 2010). First, we will study how different LLL policies are compatible with each other in terms of their orientations and objectives and how each policy considers the needs of ‘young adults’. Second, we will research the intended and unintended effects of ...
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Crucial processes within cells depend on specific non-covalent interactions which mediate the assembly of proteins and other biomolecules. Deriving structural information to understand the function of these complex systems is the primary goal of Structural Biology.In this application, the recently developed LILBID method (Laser Induced Liquid Bead Ion Desorption) will be optimized for investigatio ...
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"Data on seawater composition since the start of the Phanerozoic eon ~540 million years ago provide essential information for understanding long-term chemical processes of socio-economic dimension like the evolution of life, land-ocean interaction, atmospheric chemistry, ecosystem adaptation to climate change, oceanic trace metal cycling, and for applied geological processes like the formation of ...
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EUROPOL

Start date: Jan 1, 2015, End date: Dec 31, 2018,

NMR and MRI play unique roles in contemporary Science, from Physics, Chemistry and Biology, to clinical research and diagnosis. Despite its irreplaceable role, further progress in NMR and MRI is hampered by sensitivities that are much lower than those of alternatives such as mass-spec, or PET. The prospects of solving this problem by “bigger machines” are uncertain and of poor return, given the hi ...
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MR-guided Focused Ultrasound Surgery (MRgFUS) combines high intensity focused ultrasound for thermal ablation of diseased tissue with MR imaging to visualise the tumour and surrounding anatomy and to provide MR thermal feedback.However, MRgFUS treatment of the liver and other abdominal organs present tremendous technological challenges, including motion due to breathing and shielding of the target ...
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Attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) are frequent, chronic and highly heritable neurodevelopmental disorders. Despite their societal importance, progress in understanding disease biology has been slow and no curative treatment options are available.The pan-European training network MiND aims to educate a new generation of researchers in the field of n ...
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The increasing number of refugees and migrants within EU countries forces all stakeholders involved in language education and integration to rethink traditional concepts of language education. Successful integration of migrants, especially in participatory processes, strongly depends on learning local foreign languages and intercultural competencies, without neglecting heritage languages and cultu ...
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The latest developments in low flying unmanned robots with arms and the associated fields of intelligent control, computer vision and sensors open the floor for robotic solutions, exploitable in the near term, in the field of inspection of difficult-toaccess areas of the civil infrastructure in general and bridges in particular. The latter infrastructure is ageing requiring inspection and assessme ...
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"Chronic pain is prevalent and it causes decreased quality of life and significant costs to the society in terms of lost working capacity. Currently available analgesics are either not effective enough or patients cannot take them due to adverse effects. Non-steroidal anti-inflammatory drugs are a major cause of drug-related morbidity and mortality. Opioids can cause tolerance and addiction when u ...
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