7 European Projects Found
Searched on 125080 European Projects
FINISHED
iABC Programme (IABC PROGRAMME)
Start date: Aug 1, 2015, End date: Jul 31, 2020,
...oups combine experience and proven expertise and success in microbiology, antibiotic development, clinical trials, endpoints and patient registries. Their existing infrastructure provides an excellent basis for the successful achievement of the objectives of ND4BB Topic 7. The iABC consortium will build on and add to existing research networks and infrastructures within the IMI ND4BB-program, ther ...
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21
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Clonidine for Sedation of Paediatric Patients in the Intensive Care Unit (CloSed)
Start date: Dec 1, 2013, End date: Nov 30, 2018,
The majority of critically ill children admitted to Paediatric Intensive Care Units (PICU) will require sedation and analgesia which is commonly achieved with a combination of an benzodiazepine and an opioid. However, these agents have a significant side-effect profile, including tolerance, withdrawal and respiratory/circulatory depression. Clonidine is commonly used for sedation in PICU and recom ...
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10
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Labeling of Enalapril from Neonates up to Adolescents (LENA)
Start date: Nov 1, 2013, End date: Oct 31, 2018,
Children are often treated as small adults—not as the special patients they are. Regulations exist to encourage the development of drugs and formulation for children. However, off-patent drugs are often administered to children without appropriate formulations or systematic investigations. Therefore, the paediatric use marketing authorisation (PUMA) has been designed.The EMA Paediatric Working Par ...
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14
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PanCare Studies in Fertility and Ototoxicity to Improve Quality of Life after Cancer during Childhood, Adolescence and Young Adulthood (PANCARELIFE)
Start date: Nov 1, 2013, End date: Oct 31, 2018,
Survival rates after childhood cancer now reach nearly 80% in developed European countries as a result of more effective therapies and better supportive care, leading to a steady increase in the number of survivors in the population. However, the treatments that have improved survival are harsh and cause serious side-effects that can greatly impact survivors’ quality of life in the long term. The ...
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19
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GAbapentin in Paediatric Pain (GAPP)
Start date: Jul 1, 2013, End date: Jun 30, 2017,
Chronic pain is estimated to affect 15-20% of children with varying disabilities. Due to the paucity of clinical information and appropriate medicinal products, in clinical practice paediatric patients are often under-treated causing profound impact on their QoL.To date, opioids, non-steroid anti-inflammatory drugs (NSAIDs), antidepressants and anticonvulsants are used to treat pain, but only few ...
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16
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New Models for Preclinical Evaluation of Drug Efficacy in Common Solid Tumours (PREDECT)
Start date: Feb 1, 2011, End date: Apr 30, 2016,
Traditional preclinical discovery methods, particularly for target validation, poorly predict drug efficacy, causing a high attrition rate in costly late-stage clinical trials. The PREDECT consortium will focus on complex but transferable, next generation in vitro and in vivo models for breast, prostate and lung cancers. Models will be investigated for their improved potential to validate novel th ...
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23
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Prostate Research Organizations-Network of Early Stage Training (PRO-NEST)
Start date: Oct 1, 2009, End date: Sep 30, 2013,
"New and recent developments have revolutionized the prostate cancer research and clinical arenas, requiring the next generation scientists to have comprehensive knowledge and expertise in basic, clinical and applied research. PRO-NEST offers young researchers a European integrated, multi-disciplinary training programme to become an independent and all-round scientist and team leader in (prostate) ...
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